Chronic systemic inflammation

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tropicaldaze1950

Well-Known Member
Beyond Testosterone Book by Nelson Vergel
What is the actual science, not opinion, regarding testosterone and the reduction of systemic inflammation? My hsCRP has remained elevated for several years. Lipid panel isn't good. PSA is rising, though no cancer and gland is small and soft. My urologist believes, too, it's due to inflammation. I know, too, that testosterone isn't the end all be all for reducing systemic inflammation. I'm cutting wheat out of my diet. From my reading, it seems to be problematic in multiple ways. I've been gaining weight for years. My ideal weight should be 135. I'm now at 160. A1C is 6.6 but glucose is within normal range. Metformin gives me diarrhea. Tried it twice. Stress I can't reduce and sleep will still require medication. That goes with bipolar illness & CPTSD. Nor can I stop being the full time caregiver for my wife, now into her 3rd year of Alzheimer's.

I'm 74 and can't play games with myself. My urologist prescribed a long course of doxycycline to see if it will lower PSA and lower systemic inflammation. That antibiotic is also used in psychiatry to manage neuroinflammation. Though I'm glad he's amenable to giving it a try, if I take it and also make dietary changes, I won't know which is making a difference, though maybe I need to approach this issue both medically and nutritionally. As for testosterone, need to reduce my dose from 100 mg 2X weekly. Helped my depression, anhedonia, anxiety and ability to handle stress, but just felt like too much for me. E2 was 99 but I didn't want to add an ai. Maybe I'm too anti ai, but reducing the dose seems more sensible as I try to find an acceptable balance. To what dose or injection frequency I don't know. I know it's a matter of trial and error, but my instinct says to go with 2X weekly or maybe EOD at whatever dose I use.

Thanks.
 
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