I do subQ, it works for me.
What are the main differences between SQ and IM for you, do you really feel different?
To bring back on track:
OK, so I'm trying to wrap my head around this:
-What is it about less frequent dosing that benefits high SHBG guys? The aspect I question is the idea that lower trough helps to bring down HCT. Less frequent dosing also means higher peaks. Do they not contribute to higher HCT?
-What about more frequent dosing would cause them any issue?
-Would lower stable levels without the peaks and troughs not also help bring down HCT? This seems to be an implication in the daily administration study above.
Does low SHBG require a higher weekly testosterone dosage?
https://www.excelmale.com/forum/sho...G-require-a-higher-weekly-testosterone-dosage
I BELIEVE i read something on here from Nelson, that said it was the higher Trough levels that were correlated with higher HCT (not peak or average levels). I cannot find it now. However if that is the case, it wouldn't suggest a mechanism for daily shots resulting in an improvement in HCT as, moving to ED would lower peak values and raise trough values to resemble more of a straight-line steady state.
On a possibly related note??...I am on daily Test Cyp and when I first switched to ED injections, I kept the same weekly dosage. This brought my trough TT from around 800 to about 1300 and doubled my free T. I have since reduced my weekly dose by 15% and will be getting tested soon. I noticed my Hematocrit remained at 50.5 after 4 months of ED injections (without blood donation) when in the past it would have risen closer to 54%. The only things I changed were dose frequency and I added Grapefruit Seed Extract. Were either of these responsible/contributing factors or have I just stabilized over time?? I switched to ED because of very low SHBG and i feel much better since the switch. IF (big IF?) the frequency had any effect on HCT for me, that was just gravy as overcoming low SHBG was my goal.
Dr. Crisler advocates daily HCG shots for anyone using HCG... I was not referring to Testosterone shots. There are several posts of his on the various forums he visits supporting this.
TD's stabilize, at an even daily dose, in 3 days.
QOD shots build to a steady state, for sure.
Variables, for a given weekly dose, and comparing once per week, twice per week, and QOD, include lessening urinary excretion the shorter the injection interval. You also tend to get less estrogen conversion, and less stimulation of RBC production.
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