Deleted member 16042
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I wish there was a sticky!
I am trying to search on this topic and finding a few things, but no comprehensive discussion of trade offs between Daily vs less frequent dosing protocols, and some conflicting info. I am potentially interested based on my own needs.
A brief summary of the basics as I understand them. Please correct me if I am wrong on any of these counts and add pertinent info!
-Daily dosing could provide the most stable state of T blood levels
-There is potential to reduce total weekly dose since daily dosing provides a cumulatively higher steadier state and prevents low troughs. (Some anecdotes however contradict this.)
-Daily dosing is particularly useful for those with low SHBG. Refreshing or topping off the tank daily helps to keep free T levels up since low SHBG guys tend to pee out the free T rapidly
-For those with high SHBG, less frequent dosing can be useful, -it is theorized that a lower trough can be useful to keep HCT lower.
-However, longer intervals between doses can create more of a roller coaster effect for both T and E2. (Therefore, longer dosing intervals should be limited to 1 dose/week for high SHBG guys. )
-Vince believes that daily dosing has helped bring his HCT down and he no longer need phlebotomy/to donate blood. There seems to be conflicting info over this though with the theory that having lower troughs brings HCT down accordingly
I am trying to search on this topic and finding a few things, but no comprehensive discussion of trade offs between Daily vs less frequent dosing protocols, and some conflicting info. I am potentially interested based on my own needs.
A brief summary of the basics as I understand them. Please correct me if I am wrong on any of these counts and add pertinent info!
-Daily dosing could provide the most stable state of T blood levels
-There is potential to reduce total weekly dose since daily dosing provides a cumulatively higher steadier state and prevents low troughs. (Some anecdotes however contradict this.)
-Daily dosing is particularly useful for those with low SHBG. Refreshing or topping off the tank daily helps to keep free T levels up since low SHBG guys tend to pee out the free T rapidly
-For those with high SHBG, less frequent dosing can be useful, -it is theorized that a lower trough can be useful to keep HCT lower.
-However, longer intervals between doses can create more of a roller coaster effect for both T and E2. (Therefore, longer dosing intervals should be limited to 1 dose/week for high SHBG guys. )
-Vince believes that daily dosing has helped bring his HCT down and he no longer need phlebotomy/to donate blood. There seems to be conflicting info over this though with the theory that having lower troughs brings HCT down accordingly
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