I'm on a similar dosage (300 IU HCG EOD) and I have noticed my testicles have shrunk compared to a month ago when I was on the exact same protocol, but a different bottle of HCG. I also notice a subjective difference between now and when I was using my previous bottle of HCG. I'm using Empower HCG.
I wonder if a higher, less frequent dosage would be more reliable based on
What is the best dose of HCG? Dr Saya presents two case studies.. Based on
this study, 250 IU EOD of HCG got to within 7% of baseline intratesticular testosterone, suggesting lower doses more frequently may work -- this is why I switched to 300 IU EOD. But there is no study on testicle size and HCG, as far as I know.