Anyone here taking progesterone?

[eli]

Any feedback on progesterone

 

[Dwayne337]

Why u care about that if ur 1-test cyp protocol was amazing 1-Test Cyp - amazing results (low shbg)

looks like it was a flop. saw that coming

 

[DS3]

Any feedback on progesterone

Yep. 5 mg oral every night. I love it. Any of the anxiety I felt on TRT, as well as any of my perceived estrogen/DHT issues are gone.

 

[Cataceous]

0.6 mg injected each night. It results in better sleep and a better mood overall.

 

[Nelson Vergel]

@Gianluca

 

[eli]

Why u care about that if ur 1-test cyp protocol was amazing 1-Test Cyp - amazing results (low shbg)

looks like it was a flop. saw that coming

Lol wtf! Love your dots connections

@Nelson Vergel any reason to supply with progesterone when one can increase it by taking pregnenolone?

 

[Nelson Vergel]

Lol wtf! Love your dots connections

@Nelson Vergel any reason to supply with progesterone when one can increase it by taking pregnenolone?

That is what I am trying to prove now. I am taking 100 mg per night of a pregnenolone capsule. Got blood drawn yesterday and ran pregnenolone and progesterone by liquid chromatography/ mass spectrometry. Results next week. We will see.

 

[Gman86]

That is what I am trying to prove now. I am taking 100 mg per night of a pregnenolone capsule. Got blood drawn yesterday and ran pregnenolone and progesterone by liquid chromatography/ mass spectrometry. Results next week. We will see.

What brand of pregnenolone are u using?

what benefits have u noticed from it again?

did u try a lower dose of preg before trying 100mg/ night?

did u ever try taking it in the morning?

 

[Gman86]

Yep. 5 mg oral every night. I love it. Any of the anxiety I felt on TRT, as well as any of my perceived estrogen/DHT issues are gone.

what progesterone product are u using?

 

[Nelson Vergel]

What brand of pregnenolone are u using?

what benefits have u noticed from it again?

did u try a lower dose of preg before trying 100mg/ night?

did u ever try taking it in the morning?

I am taking this one

The reason I take 100 mg is because it is actually a low dose compared to studies.

Pregnenolone and Progesterone for Men: Pharmacokinetics and Studies

"Pregnenolone can be administered orally, subcutaneously, intravenously, intranasally, and topically/transdermally. Oral pregnenolone has high metabolism and low bioavailability.28 It is lipophilic and readily crosses the blood brain barrier. There is very limited data on the pharmacokinetics...

www.excelmale.com

After 3 weeks, I can say that I am sleeping better and my cognitive capacity (even the fluidity of my speech and accent) is better. I will know soon if this is just a placebo effect. My mood is slightly better. No bloating so far. I will know my lab results in a week (pregnenolone & progesterone both by sensitive assay).

This is a panel I created on Discounted Labs for this purpose:

Hormone Panel for Men on TRT- Comprehensive

This hormone panel for men on testosterone replacement therapy (TRT) contains upstream and downstream hormones to testosterone. TRT has been shown to decrease upstream hormones like pregnenolone and progesterone, and slightly decrease DHEA. Downstream ho

www.discountedlabs.com

I have not tried taking it in the morning. I am concerned that if in fact it increases progesterone, I may feel tired. But there is only one way to find out! I will try it in the morning.

I have to also add that I have been taking Vitamin C (1000 mg) and lactoferrin to increase my ferritin (it was sitting at 32 even though I have not donated blood in years). That may also improve energy with potential improvement in cognitive function.

 

[Gman86]

I am taking this one

View attachment 15164

The reason I take 100 mg is because it is actually a low dose compared to studies.

Pregnenolone and Progesterone for Men: Pharmacokinetics and Studies

"Pregnenolone can be administered orally, subcutaneously, intravenously, intranasally, and topically/transdermally. Oral pregnenolone has high metabolism and low bioavailability.28 It is lipophilic and readily crosses the blood brain barrier. There is very limited data on the pharmacokinetics...

www.excelmale.com

After 3 weeks, I can say that I am sleeping better and my cognitive capacity (even the fluidity of my speech and accent) is better. I will know soon if this is just a placebo effect. My mood is slightly better. No bloating so far. I will know my lab results in a week (pregnenolone & progesterone both by sensitive assay).

This is a panel I created on Discounted Labs for this purpose:

Hormone Panel for Men on TRT- Comprehensive

This hormone panel for men on testosterone replacement therapy (TRT) contains upstream and downstream hormones to testosterone. TRT has been shown to decrease upstream hormones like pregnenolone and progesterone, and slightly decrease DHEA. Downstream ho

www.discountedlabs.com

I have not tried taking it in the morning. I am concerned that if in fact it increases progesterone, I may feel tired. But there is only one way to find out! I will try it in the morning.

I have to also add that I have been taking Vitamin C (1000 mg) and lactoferrin to increase my ferritin (it was sitting at 32 even though I have not donated blood in years). That may also improve energy with potential improvement in cognitive function.

View attachment 15165

Better reply than I could of asked for. Thanks for all that. Can’t wait to see ur lab results, and curious if taking it in the morning makes any difference, good or bad.

 

[Nelson Vergel]

Progesterone posts on ExcelMale.com

 

[Nelson Vergel]

Better reply than I could of asked for. Thanks for all that. Can’t wait to see ur lab results, and curious if taking it in the morning makes any difference, good or bad.

Even my responses on ExcelMale are getting more detailed. Better focus? LOL

 

[Gman86]

Even my responses on ExcelMale are getting more detailed. Better focus? LOL

After 8 years on HRT, brain fog is the one and only symptom I haven’t been able to kick. U and bumpy’s experiences with 100mg of pregnenolone have me pretty optimistic about giving this dose of pregnenolone a try, in hopes it improves or eliminates my brain fog all together

 

[Nelson Vergel]

@Gman86 This supplement also works for brain fog (not taking it now), but take it only as needed (not every day) since some of us report low mood after discontinuing dose after daily use.

Has Anyone Used Alpha-GPC ?

Has anyone used this supplement? Oral supplementation of alpha-GPC is of interest for nootropic purposes, as it appears to have cognitive-enhancing properties (no human evidence exists to support this in otherwise-healthy youth, but it does have support in rodents) and attenuate the rate of...

www.excelmale.com

 

[DS3]

what progesterone product are u using?

Compounded from Empower

 

[DS3]

After 8 years on HRT, brain fog is the one and only symptom I haven’t been able to kick. U and bumpy’s experiences with 100mg of pregnenolone have me pretty optimistic about giving this dose of pregnenolone a try, in hopes it improves or eliminates my brain fog all together

I will say that my cognitive function appears much better now that I am taking progesterone. Give it a try if you have not.

 

[Nelson Vergel]

@Gianluca made Empower make him a 5 mg progesterone capsule since this is what they have. He also supplements pregnenolone.

Progesterone Capsules

Choose Empower Pharmacy for compounded Progesterone Capsules. The leading accredited 503A and FDA-registered 503B compounding pharmacy.

www.empowerpharmacy.com

 

[Gianluca]

Lol wtf! Love your dots connections

@Nelson Vergel any reason to supply with progesterone when one can increase it by taking pregnenolone?

@Nelson Vergel thanks for tagging!

I heard Dr Mark Gordon saying that some people may have more trouble converting Oral Pregnenolone to Allopregnenolone, in that case Oral Progesterone may help better doing so. In my experience, Pregnenolone is calming, but for example I t doesn't help with social anxiety, when Progesterone helps.


this study was done in post menopausal women, but it shows how Oral Progesterone converts to Allopregnanolone in humans.

(PDF) Pharmacokinetics of progesterone and its metabolites allopregnanolone and pregnanolone after oral administration of low-dose progesterone

PDF | To investigate the pharmacokinetics of progesterone, allopregnanolone and pregnanolone after treatment with a low oral dose of progesterone. Eight... | Find, read and cite all the research you need on ResearchGate

www.researchgate.net

 

[Gianluca]

I am taking this one

View attachment 15164

The reason I take 100 mg is because it is actually a low dose compared to studies.

Pregnenolone and Progesterone for Men: Pharmacokinetics and Studies

"Pregnenolone can be administered orally, subcutaneously, intravenously, intranasally, and topically/transdermally. Oral pregnenolone has high metabolism and low bioavailability.28 It is lipophilic and readily crosses the blood brain barrier. There is very limited data on the pharmacokinetics...

www.excelmale.com

After 3 weeks, I can say that I am sleeping better and my cognitive capacity (even the fluidity of my speech and accent) is better. I will know soon if this is just a placebo effect. My mood is slightly better. No bloating so far. I will know my lab results in a week (pregnenolone & progesterone both by sensitive assay).

This is a panel I created on Discounted Labs for this purpose:

Hormone Panel for Men on TRT- Comprehensive

This hormone panel for men on testosterone replacement therapy (TRT) contains upstream and downstream hormones to testosterone. TRT has been shown to decrease upstream hormones like pregnenolone and progesterone, and slightly decrease DHEA. Downstream ho

www.discountedlabs.com

I have not tried taking it in the morning. I am concerned that if in fact it increases progesterone, I may feel tired. But there is only one way to find out! I will try it in the morning.

I have to also add that I have been taking Vitamin C (1000 mg) and lactoferrin to increase my ferritin (it was sitting at 32 even though I have not donated blood in years). That may also improve energy with potential improvement in cognitive function.

View attachment 15165

I noticed the same with pregnenolone in regards to fluidity of speech and accent, my brain also works quicker with tasks and thinking in general

why lactoferrin to increase Ferritin? doesn't lactoferrin binds iron preventing its absorption? I believe it is found in Whey Protein as well