Adding Arimidex to TRT protocol

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Thomas1212

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Hi. I have been on TRT for a few years now. My doctor has been telling me to take Arimidex to lower my estrogen but I have been trying everything to avoid it. My current protocol is

16mg Test Cyp Daily Subq
300IU HCG mon, wed, fri

Blood level average over past few years with above protocol

Test total average 800-900ng/gl
Free test average 180-215 pg/ml
Estradiol average 50-65pg/ml

My last estradiol was 34 which is the lowest I’ve seen in a few years and no change in protocol.

My doctor continues to push 1mg Arimidex weekly which I have major hesitation to start. I have no typical high estrogen symptoms such as sensitive nipples, emotional swings or acne. I feel good but have noticed I do not have the high libido which I previously felt during my TRT protocol. I recall having very high libido when starting TRT, I wasn’t taking HCG at that time.

What would you recommend as a starting dose for Arimidex if I was to proceed? .25mg a week?

What is the minumum dosing frequency? 1 or 2 times a week?

If I wanted to micro dose are there other options besides mixing it with alcohol?

I would love to hear the results that others had with adding AI to their protocol, either good or bad. Thank you in advance.
 
Last edited:
Defy Medical TRT clinic doctor
My doctor continues to push 1mg Arimidex daily which I have major hesitation to start. I have no typical high estrogen symptoms
Your doctor is extremely ignorant and borderline insane! 1 mg Arimidex once weekly is likely to crash your estrogen, but 7 mg Arimidex per week, this is borderline medical malpractice and extremely reckless.

The lack of robust libido is most likely to do with the HCG which is known to lower sexual desire. If you’re not trying to get your wife pregnant, I would stop it.

Stop the hCG and enjoy your newfound libido.
 
Last edited:
Hi. I have been on TRT for a few years now. My doctor has been telling me to take Arimidex to lower my estrogen but I have been trying everything to avoid it. My current protocol is

16mg Test Cyp Daily Subq
300IU HCG mon, wed, fri

Blood level average over past few years with above protocol

Test total average 800-900ng/gl
Free test average 180-215 pg/ml
Estradiol average 50-65pg/ml

My last estradiol was 34 which is the lowest I’ve seen in a few years and no change in protocol.

My doctor continues to push 1mg Arimidex daily which I have major hesitation to start. I have no typical high estrogen symptoms such as sensitive nipples, emotional swings or acne. I feel good but have noticed I do not have the high libido which I previously felt during my TRT protocol. I recall having very high libido when starting TRT, I wasn’t taking HCG at that time.

What would you recommend as a starting dose for Arimidex if I was to proceed? .25mg a week?

What is the minumum dosing frequency? 1 or 2 times a week?

If I wanted to micro dose are there other options besides mixing it with alcohol?

I would love to hear the results that others had with adding AI to their protocol, either good or bad. Thank you in advance.

Hi. I have been on TRT for a few years now. My doctor has been telling me to take Arimidex to lower my estrogen but I have been trying everything to avoid it.

My doctor continues to push 1mg Arimidex daily which I have major hesitation to start. I have no typical high estrogen symptoms such as sensitive nipples, emotional swings or acne. I feel good but have noticed I do not have the high libido which I previously felt during my TRT protocol. I recall having very high libido when starting TRT, I wasn’t taking HCG at that time.


Would not even consider throwing in an AI let alone 1 mg daily which is beyond ridiculous!

Driving your estradiol into the dirt is a bad move!

If you feel great overall stick with your current protocol.

Acne is not a typical symptom of high e2, yes it can play a role but DHT let alone sensitivity of the AR to DHT is the main culprit.

Non aromatizable androgens can cause acne!

Healthy FT levels let alone T s metabolites estradiol and DHT are needed in order to reap full beneficial effects of testosterone.

Ts metabolites estradiol and DHT are needed in healthy amounts to experience the full spectrum of testosterones beneficial effects on (cardiovascular health, brain health, libido, erectile function, bone health, tendon health, immune system, lipids, and body composition).

I would tread lightly when it comes to using an AI!








I recall having very high libido when starting TRT, I wasn’t taking HCG at that time.

The key point that needs to be stressed here.....the body will eventually adapt to its new set-point and for many libido tends to wane more into what would be considered normal/healthy.



Regarding libido as I have stated numerous times on the forum over the years.

Big mistake getting caught up on that honeymoon period whether first starting T or tweaking a protocol (increasing dose of T) where it is common for one to experience a strong increase in libido/erections.

Unfortunately for many this is short-lived as the body will eventually adapt to its new set-point and for many libido tends to wane more into what would be considered normal/healthy.

Again having a healthy FT is only one piece of the puzzle as libido let alone ED are multifactorial.



Again this needs to be stressed!


*The male sexual response cycle is complex and the exact role of testosterone in mediating libido, arousal, erection, ejaculation, and orgasm is multifactorial

*This hormone isn’t the only biological factor with clear, substantial power over our libidos
 
The lack of robust libido is most likely to do with the HCG which is known to lower sexual desire. If you’re not trying to get your wife pregnant, I would stop it.
This is not an accurate characterization of hCG's effects on libido, if you are considering the totality of anecdotal data. hCG has more of a reputation for improving libido actually. There are men for whom hCG lowers libido, perhaps because E2 becomes excessive or for other reasons, but this is not the majority.

I agree with you and others that OP would be mistaken to start taking anastrazole given his lack of E2 symptoms, especially not in the monster doses he was prescribed, which would surely cause him a world of suffering.

If OP were curious if this protocol and its results could be improved, I would probably try dropping hCG to clarify how that is affecting his blood work and his symptoms. Maybe he will learn that he feels better without it, or maybe he'll learn that it was beneficial and add it back in.
 
My apologies for the type. Arimidex 1mg a week is what my doctor is suggesting.

It seems everyone agrees that I should avoid AI. I do feel good and have no high e2 symptoms that I am aware of. I want to keep HCG since I want kids in the future. Was just hoping to increase libido to the level it was previously. Morning erections are not as prevalent as they were before. I’ve also noticed an increase in having to pee at night. 1-3 times a night I have to get up when it was previously 0-1 times a night. Could this be related to TRT in any way or just getting older?

Thank you all for the help.
 
Big difference. How does he recommend you dose 1 mg/week?

Attention to detail is helpful on forums so you dont get a page of "1 mg/day of adex is nuts" on your thread.
Agreed. I corrected my post. That mistake definitely paints the wrong picture. My apologies. He said one 1mg pill a week, single dose.
 
Agreed. I corrected my post. That mistake definitely paints the wrong picture. My apologies. He said one 1mg pill a week, single dose.
So he just wants you to take a single 1 mg tab, once a week. Not ideal. If you wanted to trial maybe try 0.25 mg a couple times a week and test your dose response. I do have concerns with long term AI use, but a short experiment will give you data if you are game.

Thanks for clarifying.
 
Morning erections are not as prevalent as they were before. I’ve also noticed an increase in having to pee at night.
The hCG can cause water retention, this is most likely affecting your libido and erectile strength. You said you wanted children in the future, stop the hCG for now and restart it when you do want kids.
 
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The hCG can cause water retention, this is most likely affecting your libido and erectile strength. You said you wanted children in the future, stop the hCG for now and restart it when you do want kids.
Thank you. I will consider this more. I did have some testicular discomfort which HCG helped solve. Would lowering my HCG dose help in any way if I wanted to continue it but possibly increase libido and reduce water retention. What would be the minimum affect dose of HcG?
 
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