e2

Anyone know the difference between E2 sensitive, and E2 ultrasensitive? And which one should I get? They’re both the same price on discounted labs.com. Thanks.

Hello, does any one else here at the moment runs in the same problems as me? I’ve been trt for about 4 years now, and used about three years aromatase inhibitors, letro arimidex and aromasin, i’ve been used them all, and always caused me crushes e2 symptoms when i took them even while my e2 was...

I'm not sure how to ask my question, but I would like to know the specifics on why low shbg is such a problem in regards to elevated E2? I understand that when one is low on shbg that E2 can get out of control, my question is why administering an AI doesn't work. I'll use my self as an...

Since this question is always a hot topic on here, I did both tests at the same time to see how far apart they were, Royal paid for the non-sensitive and I paid cash for the sensitive in the same blood draw: ESTRADIOL, SENSITIVE 22.6 PG/ML 8.0-35.0 02 Methodology: Liquid chromatography tandem...

Hey all - I've been on TRT for 10 months and just found this forum today - what a MASSIVE wealth of information! I've been relying on a single thread on another forum that's totally unrelated to health, and it's been a huge help, but nothing like this. I could really use your help today; TRT...

Hi All, Can low SHBG guys comment on what is your protocol? and Whether it works successfully for libido and energy? - From what I have read and in my personal case, when E2 is low, mirroring SHBG values, it is like the sweet spot, and rationale is that the low SHBG makes too much of free E2...

Is it high E2 or low E2? - has anyone experienced it? I am low SHBG ~10-12, and if I am not in the perfect sweet spot (which typically only lasts for a few hours to a 1-2 days most), I start to have blurred vision. I know it is related to E2 because I noticed a correlation when I feel good...

Been on TRT for about 3 months now and it has been a roller coaster to say the least. I started on 125 a week split up on Monday and Thursday of each week. Also with HCG and .25 of an AI on injection days. started having bad palpitations and hot flushes. Had me double up on AI and it tanked my...

I'd like to run a little experiment and try Arimidex. Total Test 926 Free Test 23 E2 non sensitive 72 SHBG 31 Based on those labs, what amount can I get away with using without crashing my E2? Being at 72 I have some room to work with. Here are my questions: - how many times a week should it be...

Guys, is there an upper limit for estrogen aromatization? Do receptors get saturated at some point and level off with testosterone still climbing? What I'm asking is can we beat high estrogen by supraphysiological levels of testosterone and maintaining a good ratio? If my E2 is 72 with test...

Hi, is there any benefit in trying to have a steady daily anastrozole dose vs twice a week?

Since arimidex blocks the conversion of T to E2, would that mean that it drives dht higher since that's the other hormone T coverts to? If not, where does the t go? Does it get expelled or converted into something else? Also, it seems like high prolactin reduces dht by 58 percent in a study I...

Guys, is it possible to have a very high level of E2, but experience no moodiness or water retention? My E2 is over 72 but I feel fairly emotionless if that makes any sense. Almost like the symptom low E2 guys suffer. Any ideas why?

Just wanted to post about my journey to this point with TRT. Started replacement about 18 months ago. Moved to Defy about 12 months ago. Started with 72mg twice a week. .125 AI twice a week and 500 hcg twice a week While I felt generally better and had a pretty fast body recomp, I was tired...

SOOO, I added HCG to my TRT the end of may 2019;.. the first 4 weeks was 500iu a week .....i wasnst sure how my body was going to react .... so i jumped it up to 800iu the last 2 weeks of the first 6 weeks of it before my first Labs to check E2 and hema it was fine... so I jumped it up to...

A bit of a hypothetical question here, but something I've been curious about. Supposing someone with relatively normal SHBG (mid 20s-mid 30s) is on a T. Cyp. E3.5D injection protocol and has slightly elevated E2 and HCT. TT/FT slightly above range at trough. For this example, let's say they use...

I have decreased my dose on 3 occasions and I still keep hitting over 1000ng each time with a corresponding high aromatise to E2. it seems when I decrease my dose my body just seems to metabolise these substances differently. I have titrated down from 100mg of Test E and 1000iu of HCG a week to...

Hello all, My testosterone levels were 150, I was feeling like crap. Low mood, low energy, brain fog, low libido that has become non-existentant. I began on testosterone cyp low dose injections 3 times a week and was put on Anastrozole 1 mg per day.... My test went through the roof over 1500...

I'm a long time lurker and haven't posted much (perhaps even never) but I felt I should contribute something in return: I have very mild gyno that I've had most of my life. As soon as my E2 goes up it starts getting sore. That's when I USED to take an arimidex and it would go away. This time...

Gentlemen, I thought that this was interesting Currently, there is no consensus regarding the expected concentration levels of intra-prostatic sex steroids in patients with Prostate Cancer (PCa). Our objective was to assess the concentration levels of sex steroids in prostatic tissue and...

I've seen it mentioned from time to time that that T level peaks have the strongest affect on E2 and that T level troughs have the strongest affect on HCT. For example, if you want to lower E2, reduce the spikes in your T levels, which is often accomplished by more frequent injections. If you...

A discussion on another thread - and lots of other anecdotes - raises the question of injection frequency vs dosage. It is not uncommon to read about guys who lowered their E2 by switching to more frequent injections. It is also not uncommon to read that whenever a guy switches to more frequent...

So I just had an interesting thought about E2 levels in men. So the gold standard in regards to where we want our hormones, is to get them to the levels that they were when we were in our prime, correct? So probably around 18-22, I would assume for most men, hormone wise at least. Take total and...

Low Estradiol Concentrations in Men With Subnormal Testosterone Concentrations and Type 2 Diabetes This is an interesting study of men with T2 diabetes. It's interesting for several reasons outside of diabetes. 1) It directly compares the cheaper immunoassay Vs LC-MS/MS sensitive test for E2...

I am curious how other men feel with high e2 levels... What symptoms and/or negative effects you feel when your estradiol is elevated? I used to be able to run 200+mg doses of testosterone with no AI and be ok when I was like 18-20 year old.. situation changed as I got older I need to be in very...

Hello, I need to pull labs but am waiting because i have tweaked my protocol a bit. I am having no morning wood, my erections are hard but they seem not as full and my balls are tight to my body and seem smaller....wont hang. Also achy joints. To me is all high e2 sysmptoms except for achy...

Im seeking advice on how I can raise my estrogen. Its been low for over 6 months. I do my test shots twice per week(150mg total). I have tried raising my dose and also just doing one shot per week but I feel even worse if my testosterone gets to high.. So my question is- Can clomid help raise my...

I tried the search function but "DIM" doesn't contain enough characters to preform a search.... Thanks!

Hi Guys, Will this TRT journey always be an emotional roller coaster? Is it for you guys/most? Starting my 4th week of cyp injections 200mg every 2 weeks. I know I said my doc would allow weekly but when I asked he said no. So I've had 2 shots now since my 7-23-18 start date. Each time it...

Do you guys think that we should all try to get our E2 around where it was pre-TRT, or do you think our sweet spot for E2 would increase since we are increasing our testosterone on TRT. For example, pre TRT my E2 consistently was around 23-25. So it seems that my body liked to keep my E2 around...