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I was confused by this. No new discussion allowed? Does this board ban free speech? I don't follow the "youtube docs" as I find them rather obnoxious but I thought Nelson himself was skeptical of aggressive E2 management with AIs. When you "spend time with the search feature" on here you...

Your numbers are almost a carbon copy of mine to include blood levels and dosing. I was on twice weekly test shots and I take 200 IU of HCG daily. I am a high SHBG guy and have always had a sensitive E2 in the 40's. I also dealt with penis sensitivity issues that turned out to have zero to do...

Apologies for not responding to you sooner. I am not always a frequent flyer on here. You lost me on your cancer argument. Cancer patients undergo chemotherapy after they have received a definitive diagnosis and they do so to save their life. You never received a definitive diagnosis for...

My intention wasn't to initiate an internet argument on here so I cringe when I read a statement that begins with "you need to" and ends with the obligatory exclamation point for emphasis. I was merely reading the thread and reiterating the facts that the man reported. His testosterone was...

I am curious. You had a total testosterone in the normal range and were prescribed an expensive treatment for men with low testosterone which you did not have under the pretense of treating a low free testosterone which is bull because they did not know what your free testosterone was in your...

My last labs were for the following regimen: Test Cyp 80 mg q 3.5 HCG (Pregnyl) 150 IU daily DHEA 75 mg a day, 50 in the morning and 25 at night. I always have blood drawn on injection morning before injecting to get a trough. I feel optimal in every way except for libido, but I suspect that...

In my opinion (for how little that is worth) yes we should only care about free E2. Total E2 is only clinically important after we factor in the effect of SHBG levels. I have come to the conclusion after digesting this site that those of us who have a decently high SHBG are the lucky ones as...

Strongly recommend you click on the link and read that study. There is a chart of DHT levels over time that is fascinating on page 728. Interestingly DHT peak levels were the same regardless of dose. Doses were 12.5 mg, 25 mg or 50 mg. However the 50 mg dose maintained DHT levels over 16...

Correct! Dr. C is overseeing this process and counseled me accordingly but its an important thing to point out. My draws were on injection day before injection but two hours after applying the cream.

Unless your prescribing doctor utilized a test dose for you his initial dose recommendation is simply an educated guess. My advice would be not to use Trimix for the big day until you have practiced injecting and found the right dose. You don't want to miss the injection because of nerves and...

What about using both? I am expecting my initial set of labs any day now after adding 25 mg a day (one click) of Empower compounded cream applied scrotally to what I was already doing - 80 mg test cyp q 3.5 and 150 IU/day of HCG. I anticipate needing to drop my injected dose and increasing to...

Not sure how to add the link here but the study can be found on Pub Med, Journal of Andrology, titled Pharmacokinetics of Testosterone Cream Applied to Scrotal Skin. Its a very interesting study. I am changing my regimen because of it and have realized some improvement to libido and performance.

I don't know how any of you made it through more than a minute of his productions with his screaming into the microphone and verbal posturing. He could be a genius for all I know. I just find his "on" persona utterly loathsome. No doubt he has an appeal to the self-love "bro" crowd.

I should say though that I had large well developed bilateral varicoceles that required surgical removal so I assumed, rightly or wrongly, that they caused damage which led to primary hypogonadism.

I am very embarrassed to say that I never found out. The testosterone mill I resorted to did not test for FSH/LH which I regret now. I very much wish that I had known. I just had terrible low T symptoms, several tests of Total T around 400 and a Free T of five. Would my response to HCG be...

I have to concur with GMan on this one. My Pregnyl experience is backed up by significant TT increases on labs. FYI. Because of this thread I checked with my local pharmacy and as luck would have it they now have Pregnyl on the shelf again. I very happily ordered a refill.

Horrified is the proper emotion to feel in this case and your caution is justified. We men are the worst hypochondriacs when it comes to estrogen. I think many are victims of their own minds - attributing any little thing (bad workout, below average sexual experience, bad day) to estrogen when...

Interesting to me that you are experiencing that on compounded HCG from Empower. I think we may have discussed before but I may experiencing this as well. I recently added 25 mg of test cream applied to the testicles to my 160 mg a week of test cyp and 150 IU a day of HCG and had a noticeable...

Don't do it. It sounds like you are pretty committed to going down that path but I would not if I had those numbers. Depression can be due to any number of things. Using one person as an example (the MMA guy) is not a way to make that decision, for example for many people TRT has a negative...

My SHBG has always been in the mid 40's so rather high. I use 150 IU of HCG daily. My last sensitive E2 was 37 but it has run into the 40's before as well, though I have never had any E2 symptoms but I have convinced myself in the past that my lower libido was E2 related - I even procured an...

I recently added 20% cream to my TRT regimen after consulting with Dr. Crisler. I have been on TRT/HCG for almost a year and a half and have textbook numbers, TT-1000, FT-25, everything else in range, but my libido still wasn't where I wanted it. My erectile function was adequate but not ideal...

I responded dramatically to HCG to the point where I was able to reduce my test cyp dose. I use 150 IU per day and I have zero estrogen issues but I have a decently high SHBG.

Thanks for the feedback. Was just curious on the comment on DHEA dose. I checked my last labs from a month ago and my DHEA was 273 on a scale of 71-375 so not high by any means. In a consult with Dr. Crisler he actually advocated an even higher dose. Is there a downside to shooting for a...

After reading the poster and Defy customer who was put on TRT with a TT of 600 and whose only symptom was "feeling blah" I question whether they are anything more than a testosterone mill - not that there is anything wrong with that - I utilized a testosterone mill as well. You just have to...

You got screwed. If I could run a TT of 594 on my own and didn't have any symptoms of low T I can't imagine starting TRT. Six hundred is an average TT for a guy in his 40's. I had a TT of 400 but I had multiple symptoms. I'd start the PCT restart right away - but not with the doctor that...

Oh and my "prescribed" dose was 10 units.

I am in the dialing in process as well and close to where I need to be. I started very low and had a couple injections that didn't work until I got to a high enough volume. I just wanted to be very conservative and not have to go to the hospital. For me it looked like this: 5 units - nothing...

I take the DHEA and Preg with breakfast and dinner, which is about two hours before bed.

I just turned 49 so entering 50's territory. Perhaps I need to explore reducing my test cyp dose. I also might try skipping my DHEA or preg for a week or two to see if that helps. Honestly I don't know if they help or not. When I started on TRT I also started DHEA and Preg so it was hard to...

I would consider myself a TRT success story except for one thing. I have never at any time in my life had an issue with sleep but now that I have my numbers dialed in, TT of 1000, FT of 25, SHBG, E2 and DHEA all within normal range, I wake up at 3:00 AM every single night and am unable to get...

What is your SHBG? Even if you have an E2 in the 50's you can have a normal free E2 which you can crash with an AI. You would just have to run a free E2 to check. I run a high sensitive E2 with a normal free E2 because I have a SHBG in the high 40's which binds up the E2.