this is an interesting study (scroll down to table 3)
https://cyber.sci-hub.tw/MTAuMTIxMC9qY2VtLjgxLjQuODYzNjM3MQ==/hobbs1996.pdf
Here, nandrolone doesn’t lower SHBG as much as I’d have thought or perhaps it is testosterone that dropped SHBG by a ton in test subjects. 6 weeks, both drugs at...
Or maybe you should start everything back from scratch... I’m always confused when guys don’t treat low SHBG extremely seriously. Perhaps because they don’t like being told that they’re fat and their diet is awful. I don’t know.
low SHBG = exaggerated metabolism and disposal of testosterone...
I’d totally go on the other “side of the fence” in a heartbeat if SPECT scans of actual living human arteries showed improvements in vascular function / blood flow (not “my” theory, real peer reviewed photographs) upon switching from a high carb diet to a high protein&fat diet. Greger is...
animal doses / human equivalent doses. “Come on”.
Triglycerides are higher on a caloric surplus. Lipoproteins are higher on a high fat diet.
The high fat dietary kool aid has people believing that the fat they eat isn’t impairing their health at all starting with blood flow. Well, I’m still...
Hahaha well perhaps people are too quick to label their one or two days of relaxing as OMGDECADICK. There are so many dudes out there popping viagra and cialis, I guess it comes with the mindset of “optimizing”.
What’s optimal, being hornier than a teenager? Like I get it people want their...
You’re using a lot of words to say that if SHBG is lower, total testosterone is lower. Because of SHBG prolonging testosterone’s half life in the serum.
I’ll be curious to look at the effect of such a small dose of Deca on OP’s SHBG
That’s not what I said.
On average, you clear testosterone much faster whenever it is released because of the absence of SHBG that would otherwise bind test and prolong its half life. I wouldn’t be surprised if their SHBG is halved or more, meaning that test is halved or more.
Now that I’ve read that DHN is basically as weakly androgenic as testosterone itself (from that study with relative binding affinities where DHN = 1, Nand .3, DHN .12, Test .1/.2) it seems to me that this Deca d*ck is very similar to the Finasteride/Dutasteride d*ck and the solution would be to...
No I meant tanked. Typically, very low SHBG (which Deca lowers) increases testosterone clearance a lot. A LOT. Ergo, levels drop fast after reaching their peak. Which is definitely not 7 days post injection ha.
It’s possible that your SHBG is shot (because of nandrolone) which increases clearance of all sex hormones significantly. Looking forward to your results there.
the more I read various topics the more I think it’s low SHBG from 19nors that CAN make testosterone such a nightmare because of its...
Just bump up your test by 50% and see how the stack goes. Don’t tweak 2 variables at once. 25 mg of Deca seems very low but your doc must have experience with it.
FWIW. Here’s some rat science that may or may not be relevant for hair regrowth? I know Taeian has made some bold claims regarding Deca regrowing hair. To his defense he does have pretty solid hair, and all of the golden era guys did as well.
Estrogen Receptor Alpha, but Not Estrogen Receptor...
Yeah that’s my intuition as well. That Dr O’Connor patient had E2 down to 6 and reported no side effects, but their SHBG was even lower iirc.
I’m always wondering how much of all this is about androgen/estrogen ratio (DHN is weak, so low E2 is sufficient to balance it out?), whether estrogen...
Yeah I’ve got quite the list of commonly used products that lower e2. I’m even suspecting red meat to cause issues because of all the zinc (Natural AI?). Might be a bit extreme here I’m not sure. There must be a reason why I don’t enjoy beef as much as chicken, milk, fish ha. I’ve also had...
Thank you for your message I appreciate it. I was being sarcastic about what’s a libido, meaning I had absolutely no desire ie. “libido?? Me? Haha no”.
yeah Clomid was a massive failure unsurprisingly. Found a bloodwork after 3 weeks on it, total Test was higher but free T was... 2.9pg/mL. So...
like I said, your SHBG must be brought back up. TRT and HCG fail to address this problem and will cause exaggerated metabolism of testosterone into its (excessively) androgenic metabolite DHT and estrogenic metabolite E2.
losing 10-15% bodyweight was also shown in androxal’s documents to...
You must get SHBG back up. Your free T / total T ratio isn’t off so I’m positive that you’ll have everything going back up with SHBG.
it seems to me that Clomid is your best bet. Clomid shoots SHBG back up while having an anti estrogenic effect. This will drop prolactin, increase total and free...
I was reviewing blood tests from back when I was still natural in 2016. Total T in the 800s, single digit free T (pg/mL), E2 around 10 pg/mL. Then I started using steroids for about 18 months, hopped off. Total T in the 600s, free T and E2 around 12 pg/mL. I’m 10% fat year round. I’ve tried...
I’m stubborn ;) here’s the study where nandrolone showed enhanced collagen type 1 deposition
Nandrolone Decanoate Determines Cardiac Remodelling and Injury by an Imbalance in Cardiac Inflammatory Cytokines and ACE Activity, Blunting of the Bezold-Jarisch Reflex, Resulting in the Development of...
I think it's safe to say that prolactin goes up as estrogen content in tissue goes up.
Perhaps it's the increased free E2 from 19nor use, since SHBG can drop to single digits. I'm not sure.
The abstract below got me wondering - Perhaps it's nandrolone itself being estrogenic with cumulative...
While I'm at it with this one study:
It's always funny when placebo groups have the worst side effects. One guy did report sexual issues. Perhaps he spent too much time reading about Deca dick? ;)
Just in case this study flew under the radar among all of @Nelson Vergel shared papers in his sticky.
Effects of Resistance Exercise Training and Nandrolone Decanoate on Body Composition and Muscle Function among Patients Who Receive Hemodialysis: A Randomized, Controlled Trial
so much for...
I’m positive nandrolone increases type 1 collagen, which is great for skin scalp etc.
those men (doses used here are no joke) sure seem to use a lot of test, Deca, dbol and HCG and have increased type 1 & 3 collagen...
I’m positive Oxandrolone is over the top here: “pure” androgen, drops SHBG really low (which frees up a lot of DHT), is infamous for smashing HDL and perhaps kidney function which explains your potassium being slightly off.
I’d drop it
This comes from the very biased, cherry picked science showcased by Dr.Greger on his channel. I hate the guy but I can’t deny published visuals that happen to align with my experience eating certain macros over others.
Scans 3 minutes in, if you can’t stand his voice :)
I didn’t do an OGTT...
There’s also this study I’d like to share, although their assessment of androgenic potency may or may not be the be all end all methodology...
Different Binding of Testosterone, 19-nortestosterone and Their 5 Alpha-Reduced Derivatives to the Androgen Receptor of the Rat Seminal Vesicle: A Step...
that's very valid.
In the study below, nandrolone (150mg e14d) improved quality of life and fared better in various aspects of sex function compared to placebo, but not 100% bulletproof.
https://academic.oup.com/jcem/article/90/8/4474/2838433
this second study also showed better quality of...
This site uses cookies to help personalise content, tailor your experience and to keep you logged in if you register.
By continuing to use this site, you are consenting to our use of cookies.