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Do you find that it makes a difference whether you take it with or without food?

Thanks everyone. Does taking it 2x daily seem to keep you covered all day (erection-wise). I'm debating whether to spread my doses out to 2x or 3x daily. if 2x covers all day I guess there's no need to do 3x.

I've been scouring the internet and finding conflicting answers on this. My bottle (NOW brand) says to take between meals. Examine.com says "To supplement L-citrulline for circulatory health or to alleviate erectile dysfunction, take 1,000 mg of citrulline, three times a day with meals, for...

The law in my state says that no prescription is required for syringe purchases. Every pharmacy I've tried has either refused to sell them to me without a prescription or limits me to 10 at a time. Except for the Wal-mart pharmacy. Apparently Wal-mart has a company-wide policy of freely selling...

Correct. Depending on what my T and E2 levels are at the time I either can't get it up at all during the day, or can only get it halfway or so and then lose it quickly. During these same times I wake up at night with rock hard erections but they go away quickly once I'm fully awake.

No idea. I've never had it tested. Is cortisol something that could cause daytime ED while still having morning erections?

I know that's the standard advice, but I don't think it's the case here. When on Cialis and dialed in on TRT perfectly things work well during the day. Does anyone know of any physiological reason that I'd get consistent, good nocturnal and morning wood but not function well during the day?

I've noticed this when I was having ED problems before starting TRT and almost every time when I have problems while on TRT. There have been times on TRT when my levels were way off and I didn't even get morning wood, but most of the time when my levels are good or close to it I get great...

Does anyone know if it matters whether I take L-tyrosine with or without food? Can I take it right at bedtime or will it keep me awake?

Has it had any effect on erections? Any premature ejaculation? (If you don't mind over-sharing haha).

0.75mg isn't anywhere close to 0.08mg. I think you misread the dosage. It wouldn't be possible to accurately split a 1mg tablet into a 0.08mg dose. Anyway, Dr. Saya recommended against using this method (dissolving in vodka) citing that there was too much potential for inaccurate dosing, so...

I just spoke with someone at the office and he's going to get your approval and then put the order in for me with overnight shipping. Thanks again for all of your help with this! You've really gone above and beyond and I appreciate it. Stay safe with the tropical storm/hurricane!

I'm switching to a dose of 0.08mg anastrozole daily. I'd like to get started on that new dose asap before the new compounded capsules come in the mail. I have some leftover 1mg anastrozole tablets and I've read various accounts of people dissolving them in vodka to get accurate microdoses...

Thanks so much! I've emailed Defy for authorization of the new 0.08mg Anastrozole dosage, and I'll get started on that asap. I'll also start L-Tyrosine at 500mg BID. I still have some 0.1mg anastrozole capsules left over from before. I previously felt much better on 0.1mg EOD than I feel now...

Interesting! What specific symptoms has the L-Tyrosine helped for you?

Thanks! I'll start the L-Tyrosine now. I think I'm the guy you think I am. We've discussed that I'm extra sensitive to swings in E2, to general E2 level, and also that I'm very sensitive to HCG and slight changes in HCG dosage cause big changes in Total T. My latest labs (while on 0.05...

Thanks Dr. Saya and everyone for replying. Dr. Saya, I have an appointment scheduled with you for September 27. Is there anything you can recommend for me to try between now and then to try to get back on track? I'd rather not wait until the 27 to start feeling better if at all possible. Should...

The only SHBG and DHT results I have aren't recent. They're from before the results shown in my original post. The results were: 8-27-2014 - SHBG: 41 (just before starting TRT. T level was 261). 3-31-2015 - SHBG: 51 (on TRT, but prior to the results listed above.) TT was 1285, FT was 25.4, E2...

I'm a Defy patient and waiting for my appointment with Dr. Saya in a month or so. I'm feeling pretty bad and hoping to get some suggestions and answers from the community here or maybe from Dr. Saya if he's around and sees this. I've been on TRT for over 2 years now, with Defy for around 10...

ZMA knocks me right out. I'm pretty sure it's the magnesium that does it, so you'd probably get the same effect with just magnesium.

The 1% Nizoral works great for me. I lather up the affected area every day in the shower, leave the lather on for 5 minutes, then rinse off.

Very interesting. Thanks! Is there an Estradiol number that you feel is the upper limit for a man with around 1100 total T (the "high end of natural")? Or do you feel that the numbers don't matter and we should only be watching symptoms, regardless of how high the Estradiol level gets?

Ok, now I'm curious! I assume this means that you and Dr. Saya have different opinions on this? Can you give us the Cliff Notes version of what you and Dr. Saya would consider high estradiol?

Pill splitters work ok, but with tiny pills like arimidex I've found it more precise to use a very sharp X-acto knife on a tabletop. You can also get capsules of your exact dosage made up at compounding pharmacies if you don't want to bother with splitting them and want to make sure you're...

I'm going to try this. Thanks! I've always had funky shoulders with poor range of motion and they're very easy to injure if I don't watch my form like a hawk when lifting. Something else that's helped me a lot are shoulder dislocations: https://www.youtube.com/watch?v=33P5AI27eiU

I've had great success using Nizoral (1% ketoconazole) shampoo to control the acne and oily skin I get on my back with TRT. I rub the lather all over my back and any other problem areas once per day in the shower, leave it on for 5 minutes, then rinse it off. I notice a huge improvement when I...

Thanks, Fireproof. This is great info.

Interesting read. Thanks! It's encouraging to see that you're doing well with no AI. I seem to be very sensitive to arimidex and get large swings from one day to the next, even with EOD Arimidex dosing. I'm trying every day now. I haven't had new labs yet, but it's been 4 weeks and I still have...

I'll definitely get two consecutive days (Cyp injection day and non Cyp injection day). What I'm wondering about is the time of day to catch the estradiol trough level. I definitely "feel" that my estradiol is higher in the morning before I take my daily arimidex pill, then it "feels" lower 6-8...

That would give me my peak and trough T levels, but I'm looking for peak and trough estradiol levels and I think they'd be at different times. My thinking is that: Peak estradiol levels would be 24 hours after test injection (highest serum T level), just before taking the daily Arimidex (lowest...

I'm not taking 0.5mg of Arimidex daily, I'm taking 0.05mg of Arimidex daily - a total of 0.35mg per week. Ive been on this protocol for 4 weeks now so my levels should be stable. I'm having intermittent issues that I suspect are estradiol related. I'd like to get labs done to show peak and...