I was sitting here thinking that much of the regenerative and restorative work is done by IGF-1. IGF-1 is produced in the liver and production is simulated by rising GH levels. So HGH is going to have to go systemic and enter the blood stream in order for the liver to produce IGF-1. So while GH concentrations might be higher in the synovial fluid, it it going to have to enter the blood stream and go systemic before the resining levels can stimulate the liver to make IGF-1?
Then comes this video. At the end the doctors says rodent studies show it doesn't matter if you go IA or sub-q to get the same effect in the joint (see 1:50min).
Dunn's protocol now is 4iu once a week for 6-8 weeks. It is going to be hard to get many side effects other than higher IGF-1 levels from this small amount.
Here is another video using BPC 157, 10,000mg!!!!