Sildenafil/Clomipramine Combo Boosts Outcomes in Premature Ejaculation

[madman]

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Sildenafil/Clomipramine Combo Boosts Outcomes in Premature Ejaculation

A phase 3 trial reveals a combination therapy for premature ejaculation significantly enhances treatment outcomes.

www.urologytimes.com

Key Takeaways​

• Combination therapy of sildenafil and clomipramine significantly improves ejaculatory latency time and patient-reported outcomes in men with PE compared to monotherapies.

• The phase 3 trial involved 795 men across 24 sites in Korea, showing greater efficacy of combination therapy in improving IELT, PEP, and PGIC scores.

• Safety data revealed mild to moderate adverse events, with no significant differences between groups, and no serious treatment-emergent adverse events reported.