Mohit Khera, MD, MBA, MPH, joins the Erectile Dysfunction Radio Podcast to discuss the use of PDE5 inhibitors for treating erectile dysfunction this week. PDE5 inhibitors such as sildenafil (Viagra), tadalafil (Cialis), and vardenafil (Levitra) are often prescribed to treat erectile dysfunction...
Phosphodiesterase 5 (PDE5): Structure-function regulation and therapeutic applications of inhibitors ABSTRACT Phosphodiesterase 5 (PDE5) is one of the most well-studied phosphodiesterases (PDEs) that specifically targets cGMP typically generated by nitric oxide (NO)-mediated activation of the...
Systematic Review of Oral Combination Therapy for Erectile Dysfunction When Phosphodiesterase Type 5 Inhibitor Monotherapy Fails INTRODUCTION: On-demand phosphodiesterase type 5 inhibitor (PDE5i) monotherapy is a first-line treatment for erectile dysfunction (ED), but 30%-40% of patients...
The efficacy of PDE5 inhibitors alone or in combination with alpha-blockers for the treatment of erectile dysfunction and lower urinary tract symptoms due to benign prostatic hyperplasia: A systematic review and meta-analysis - Abstract INTRODUCTION: Erectile dysfunction (ED) and lower urinary...
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