Wife has been on HRT for about 4 months now and I can definitely relate to what you said here about being stabbed in your sleep lol. This brings back memories of when she would get her period. I don't miss those days. I have a feeling its the estrogen that flips the bitch switch and not the T. Libido is good but she's very bitchy lately. She may have to back off the EMy wife is 55 and post menopausal. She also went to defy for dryness, lower libido. Not so much brain fog and energy. They started her on a similar cocktail. Dude I was afarid to close my eyes and sleep thinking she was going to stab me in the gace with a spoon or something! She backed off everythuand just went progesterone and things sorted themselves out. Good lubrication and libido returned. She has blood work due and is pretty sure her estrogen is going to come back near zero based on the level it has been dropping. So she may add some stuff back in.
My advice to her and you, based on my experience with others and defy, is not to start too many things at one time. If things go great or poorly, how do you know which of the additions is responsible. My new philosophy on all of this is start low and go slow. Just my 2 cents. I wish you well