WHAT MEN SHOULD KNOW ABOUT TESTICULAR SHRINKAGE AND TESTOSTERONE THERAPY

[madman]

If you're considering testosterone replacement therapy, understanding its effects on testicular size is crucial. Learn why shrinkage occurs, the treatments available to mitigate this side effect, and why testicle size usually has minimal impact on your overall health. Urologist John Smith, MD, delves into these aspects to provide a comprehensive view.


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What Men Should Know About Testicular Shrinkage and Testosterone Therapy

Considering testosterone replacement therapy? Understand its impact on testicular size, treatment options for mitigating shrinkage, and why it's usually a minimal health concern.

healthcare.utah.edu

 

[madman]

Male infertility due to testicular disorders

Male infertility due to testicular disorders Aditi Sharma, Suks Minhas, Waljit S Dhillo, and Channa N Jayasena Abstract Context: Male infertility is defined as the inability to conceive following 1 year of regular unprotected intercourse. It is the causative factor in 50% of couples and a...

www.excelmale.com

As you can see the abundance of seminiferous tubules/germinal epithelium (where sperm is produced) accounts for 80% of testicular volume.

The use of exogenous testosterone will shut down the HPTA/LH/FSH/iTT (intratesticular testosterone) resulting in atrophy of these tubules.

Now you can see why atrophy of the testes can be significant in some cases when using/abusing testosterone/AAS.

Fig. 9 Testicular atrophy in a 30-year-old AAS abuser (right) compared to normal size (left)

What is the best dose of HCG? Dr Saya presents two case studies.

It depends on why someone’s using it. If you’re just trying to maintain testicular function for the purposes of fertility and to prevent atrophy if you ever decided to quit TRT, you don’t seem to need that much. 250-500iu’s a week split up into at least 2 injections seems fine for that. You can...

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Sperm Maturation and Fertilization

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Fertility maintenance or restoration in men before, during, and after TRT or AAS

Fertility Preservation in Hypogonadal Men (2018) Robert J. Carrasquillo and Ranjith Ramasamy Introduction Testicular failure is defined as the impairment or loss of both the endocrine functions of the testis (production of testosterone, or T) and exocrine function (production of...

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[madman]

Figure 2: Ontogeny of the evolution of testicular volume from birth to adulthood. Seminiferous cords (Sertoli cells + germ cells) are the main component of the testes. From birth and during the prepubertal period (i. e., until 9–14, Tanner stage 1), the volume of seminiferous cords is determined by Sertoli cells, whereas germ cell proliferation determines testicular volume during puberty (i. e., Tanner stages 2 to 5) (adult spermatogenesis). This Figure was modified using BioRender (Scientific Image and Illustration Software | BioRender) under the authorization of[1]. © 2019 Elsevier Ltd

 

[Nelson Vergel]

HCG plus TRT to Prevent / Reverse Testicular Shrinkage and Decreased Fertility

Human Chorionic Gonadotropin (From the book Testosterone: A Mans Guide, amazon.com) Short podcast: hCG: What Every Man Should Know Human chorionic gonadotropin (HCG) (not to be confused with human growth hormone, or HGH) is a glycoprotein hormone that mimics LH (luteinizing hormone), produced...

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[Nelson Vergel]

PODCAST (9 min): Testicular Shrinkage and hCG