What is TRT and What is NOT TRT

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Hashimoto's is an autonomic disease? High vibration diet?

Wow, where have I been?

What's 99 bucks a month here and 19.99 there?

Judah channel for the win!

https://youtube.com/@thejudahchannel
Can I buy an angel to help @RobRoy understand the basics of optimization, tradeoff, and human physiology?

Maybe another bonus if the angel can help him understand blood viscosity.


Wow I missed my calling. I do all this for free lol.
 
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Defy Medical TRT clinic doctor
@RobRoy...


@RobRoy .....

?????

Nothing?

And again if you ever come across this Joseph Hearnshaw....I have never claimed to have anything to do with you and have never met or spoken/interacted with you. Not sure where @RobRoy is getting any of this.

My only thought is you have put together some PK profiles here:

So @RobRoy must have thought we are same person. But they don't include first order absorption plus elimination. Hence not quite as realistic as some I have done. The ones you did will overestimate peak to trough ratio.

Peace out Brethren. There is really nothing more humanly possible I could do within reason to engage any more substantively in this "debate". Just a hobby for me that has taken up too much time.

Best wishes as you sort through all this for yourself.
@RobRoy...


@RobRoy .....

?????

Nothing?

And again if you ever come across this Joseph Hearnshaw....I have never claimed to have anything to do with you and have never met or spoken/interacted with you. Not sure where @RobRoy is getting any of this.

My only thought is you have put together some PK profiles here:

So @RobRoy must have thought we are same person. But they don't include first order absorption plus elimination. Hence not quite as realistic as some I have done. The ones you did will overestimate peak to trough ratio.

Peace out Brethren. There is really nothing more humanly possible I could do within reason to engage any more substantively in this "debate". Just a hobby for me that has taken up too much time.

Best wishes as you sort through all this for yourself.
You better not leave!!All seriousness most of us here appreciate the time and effort you put into this. this thread has been phenomenal . I honestly hope it keeps going. Just wish @RobRoy would stay engaged. Still a lot of questions asked that he hasn’t answered.
 
With so much uncertainty on the topic and doctors (specifically hormone specialists) not even sure of the long-term safety, most times, the best treatment is no treatment at all. I wonder what percentage of doctors would agree to this statement. I bet it’s the vast majority.
I think you’re giving a lot of these drs too much credit. Look at all the other shit they prescribe without a care in the world. While I do agree testosterone had this stigma Attached to it and drs in the past shied away from it. Seems like that’s changing big time.
 
With so much uncertainty on the topic and doctors (specifically hormone specialists) not even sure of the long-term safety, most times, the best treatment is no treatment at all. I wonder what percentage of doctors would agree to this statement. I bet it’s the vast majority.

Plethora of data indicates hypogonadism is a real health problem. But if you don't have low T then you make a good point that intervention may be more trouble than it is worth.

However, now we have a new offshoot of TRT that can be many things to many people. We should learn a lot in the coming years from these experiments (unfortunately they are not RCTs). While it does not have much (any) chance of being approved I think a TOT style TRAVERSE II study with higher/supra Test dosing would be instructive.
 
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Holy shit Brother. Get well soon. I always wondered if this had ever happened to someone I just wish it had not happened to you.

You are just too fuc*ing powerful for the toilet. Jesus.

I have had so many lacerations that were life threatening. I feel your pain seriously. Glad you made it.
@readalot I probably bled out two bags of blood all over the floor. Every time I would move there would be another huge pool of blood. My wife finally wrapped a tight tape around my leg and then wrapped it in Saran wrap so I at least could drive to the hospital without ruining the car. I was just hoping I would remain conscience driving to the hospital.

Good thread so far. I am glad @RobRoy came back, I just wish we could keep the conversation going. I think it best we all are able to read both side of this and be critical thinkers. No one here is not smart enough make up their own minds.

After reading some of Crisler's old threads on here and PM I realize that this is a very new field and Crisler knew even then that we are all so very individual. Even with our response to dosing.
 
Plethora of data indicates hypogonadism is a real health problem. But if you don't have low T then you make a good point that intervention may be more trouble than it is worth.

However, now we have a new offshoot of TRT that can be many things to many people. We should learn a lot in the coming years from these experiments (unfortunately they are not RCTs). While it does not have much (any) chance of being approved I think a TOT style TRAVERSE II study with higher/supra Test dosing would be instructive.
I believe and it seemed that the late Dr. Crisler believed that what is considered as low may not be the same for everyone. If you display low T symptoms you need to be treated. As far as these very large doses, you might have good blood work but what is going to happen down the road if you continue. But then I understand athletes willing to put it all on the line and do wat you have to do to win. BBing pays a whole lot of money at the pro end. So its the same decision a guy who drives a drag racer has to make, you may end up dead. You have to be the one who makes that choice.
 
@readalot I probably bled out two bags of blood all over the floor. Every time I would move there would be another huge pool of blood. My wife finally wrapped a tight tape around my leg and then wrapped it in Saran wrap so I at least could drive to the hospital without ruining the car. I was just hoping I would remain conscience driving to the hospital.

Good thread so far. I am glad @RobRoy came back, I just wish we could keep the conversation going. I think it best we all are able to read both side of this and be critical thinkers. No one here is not smart enough make up their own minds.

After reading some of Crisler's old threads on here and PM I realize that this is a very new field and Crisler knew even then that we are all so very individual. Even with our response to dosing.
Dear Brother I have some nutty stories of bleeding out. You were very fortunate you had your wife there and she knew what to do!

I am so glad you are OK. What the hell, were you trying to Randy Savage that thing from the top turnbuckle?

We will try to keep it going with Robroy. I surely give him plenty of time. I understand you guys want to create an inclusive environment but I don't think you guys quite understand how he "debates". Nevertheless message delivered. I will turn down the dickheadedness.

There is always hope. I have offered a cease fire with him many times.
 
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Next edition of TOT Roundtable...


Sorry just too funny. Real Men!

It's Wednesday...you know what that means.

My new guilty pleasure....watching these episodes while downing my tuna or sardines and yelling "Fire it up, Fire it up!"
 
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Jay doesn't seem to even understand his cream has testosterone not test ester ... 15:10-15:30

"Remember the way that the cream cleaves as testosterone ester....it is very short half life!"


"Remember it HAS to be 200 mg/gram" wink wink!

"Be a knower not a believer."

Fire it up! FIRE it up!
 
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@RobRoy et al


Open invitation to correct your oversimplified and misleading message regarding erythrocytosis.

Distance yourself from this video and state it clearly...


Surely this is worth a podcast and deep dive as compared to a hand wave and digression into politics. Do you have the depth to go there (fluid mechanics, physiology, knowledge of the hematology literature)?

If not, no worries I have laid it out there for you. I have never heard you mention the words plasma viscosity once when dealing with this issue.

Your patients and listeners deserve the facts. How about talking about various patient subgroups that may go on Test therapy and the concerns with each rather than painting everyone with the same wide brush.


This does not cut it...


39:00

You would get a D in my class. Are you purposely misleading or really ignorant of the complete body of scientific literature on this subject.
 
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I can see why you don't like these guys @RobRoy. Still no response to above.


LMAO. I think he was laughing at you guys.

Unfortunately he doesn't understand SHBG is not driving testosterone clearance. Some association but not causation. Still repeating that high SHBG / low SHBG need different doses to achieve reasonable FT levels. It ain't because of your SHBG.

Hat tip to @Cataceous as always.
 
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I can see why you don't like these guys @RobRoy. Still no response to above.


LMAO.

Unfortunately he doesn't understand SHBG is not driving testosterone clearance. Some association but not causation. Still repeating that high SHBG / low SHBG need different doses to achieve reasonable FT levels.

Hat tip to @Cataceous as always.


Of course I have never heard of this guy either. Is he for real or is this a joke? The end with the hand hitting the chest was too much. It was hard for me to listen to this guy even fast fowarding.
 
You definitely know him better than I do. But I do think guys here want to see this debate keep going.

I guess he put that stuff at the end so you were all ready bored to death listening to him and didn't hear him.

Of course I have never heard of this guy either. Is he for real or is this a joke? The end with the hand hitting the chest was too much. It was hard for me to listen to this guy even fast fowarding.
Testosterone guru wasteland. Hey isn't that a song?

Hey I want to see it keep going to. Just amusing myself until @RobRoy appears again. Tick tock. I am here.
 
A guy I know was passing around the password to get into O'Conner's chat app. He said it is well worth listening to. I know another guy who is actually paying.

So I looked in on some of his latest videos and this app appears well done. Just great he is trying to educate on risks.

This had me laughing pretty hard.



Too bad he doesn't make some of the writing legible. Everyone always trying to pimp MIT haha.

O'Connor is excellent for this type of work as he is not encumbered with ego and theoretical knowledge from a chemical/physiology/scientist/engineer standpoint. Helping guys much more effective when the intermediary plays a helpful therapist role who on his own is not haughty or dangerous. Just relaying information.

That AAS cycle approach looks a lot like what @Gman86 mentioned. Obviously Not TRT but nice he provides some context. Spiritual guru meets androgen use. The Anabolic Doc does crack me up.
 
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I agree with you @tareload O'Conner seems to be the best of the video guys. He just presents the facts as we know them good or bad. I am starting to agree with @Charliebizz that these TRT docs may be fighting to get patients. They all sure do spend a lot of time making Youtube videos.
I actually called Kominiareks practice a few years ago about joining, I ended up not wanting to pay the membership/management fee, but he did personally call me to try to get me to join, left messages, etc. It wasn't until later that I thought it odd that a guy who claims to have thousands of patients had time to make hard sales calls.
 
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