Nelson Vergel
Founder, ExcelMale.com
Jay A. Brieler, MD, of Saint Louis University School of Medicine, evaluated electronic medical record registry data of ambulatory primary care visits from 2008 to 2013 on 1,399 adults (mean age, 61.6 years) with type 2 diabetes, with depression (n = 265) and without depression (n = 1,134), to determine the effect of antidepressant medication on glycemic control. Forty patients with depression were untreated, and 225 received antidepressant medication.
Jay A. Brieler
Fifty-one percent of patients with diabetes who were treated had controlled HbA1c values compared with 42.7% of those without depression and 34.6% of those with depression who were not treated.
Compared with patients with untreated depression, those treated were twice as likely to have controlled HbA1c (OR = 1.95; 95% CI, 1.02-3.71). Glycemic control was more likely among patients without depression compared with those with untreated depression (OR = 1.37; 95% CI, 0.74-2.54).
Anxiety disorder (OR = 2.12; 95% CI, 1.31-3.45) and age (OR = 1.01; 95% CI, 1-1.02) were positively associated with glycemic control. Prescription of insulin (OR = 0.17; 95% CI, 0.28-0.49) and prescription of any other diabetes medication (OR = 0.37; 95% CI, 0.28-0.49) were negatively associated with HbA1c control.
“Our data indicate that pharmacotherapy for depression in type 2 diabetes is associated with better glycemic control. ... This study suggests that the investment of resources in research utilizing this clinical epidemiologic approach is warranted, perhaps for analyses of larger and independent data sets. Finally, our results support the emphasis on recognition and treatment of depression in diabetes by clinicians in the primary care setting.
http://www.healio.com/endocrinology..._medium=email&utm_campaign=endocrinology news
Fifty-one percent of patients with diabetes who were treated had controlled HbA1c values compared with 42.7% of those without depression and 34.6% of those with depression who were not treated.
Compared with patients with untreated depression, those treated were twice as likely to have controlled HbA1c (OR = 1.95; 95% CI, 1.02-3.71). Glycemic control was more likely among patients without depression compared with those with untreated depression (OR = 1.37; 95% CI, 0.74-2.54).
Anxiety disorder (OR = 2.12; 95% CI, 1.31-3.45) and age (OR = 1.01; 95% CI, 1-1.02) were positively associated with glycemic control. Prescription of insulin (OR = 0.17; 95% CI, 0.28-0.49) and prescription of any other diabetes medication (OR = 0.37; 95% CI, 0.28-0.49) were negatively associated with HbA1c control.
“Our data indicate that pharmacotherapy for depression in type 2 diabetes is associated with better glycemic control. ... This study suggests that the investment of resources in research utilizing this clinical epidemiologic approach is warranted, perhaps for analyses of larger and independent data sets. Finally, our results support the emphasis on recognition and treatment of depression in diabetes by clinicians in the primary care setting.
http://www.healio.com/endocrinology..._medium=email&utm_campaign=endocrinology news
