The Amazing Bremelanotide PT-141 (Vyleesi)

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Bremelanotide PT-141 is a promising treatment option for men experiencing sexual dysfunction, particularly those struggling with low libido and erectile issues. This synthetic peptide works differently from traditional ED medications like Viagra or Cialis, targeting the nervous system rather than the vascular system[1][2].

## How It Works

Bremelanotide PT-141 activates melanocortin receptors in the brain, specifically MC3-R and MC4-R[2]. This activation leads to:

- Increased sexual desire and arousal
- Enhanced erectile function
- Improved mood and confidence

Unlike PDE-5 inhibitors that increase blood flow to the penis, PT-141 works through the nervous system to stimulate sexual desire directly[1][4].

## Benefits for Men

The potential benefits of Bremelanotide PT-141 for men include:

- Increased libido and sexual appetite
- Stronger and longer-lasting erections
- Enhanced sexual performance
- Improved overall sexual satisfaction
- Potential mood enhancement

Some men report experiencing these effects within 45 minutes to a few hours after administration, with effects lasting up to 72 hours[3][4].

## Administration and Dosage

Bremelanotide PT-141 is typically administered via subcutaneous injection, usually in the lower abdominal area or thigh[1][3]. The recommended dosage is about 1-2mg, taken approximately 45 minutes before sexual activity[1]. It's important to note that PT-141 should not be used more than 2-3 times per week[3].

## Safety and Side Effects

While generally considered safe, some potential side effects of PT-141 include:

- Nausea
- Flushing
- Headache
- Temporary increase in blood pressure

It's crucial to consult with a healthcare provider before starting PT-141 treatment, especially for individuals with pre-existing health conditions or those taking other medications[3][5].

## Conclusion

Bremelanotide PT-141 offers a novel approach to treating sexual dysfunction in men by addressing both the physical and psychological aspects of arousal. While more research is needed to fully understand its long-term effects, early results and user experiences suggest that PT-141 could be a valuable option for men seeking to improve their sexual health and overall quality of life[6].

Citations:
[1] https://www.towerurology.com/mens-health/bremelanotide-pt-141/
[2] PT-141 For Erectile Dysfunction | Brandeis MD - Male Rejuvenation Center
[3] PT-141 for Men - How to Take and Use PT-141 Peptide Injection
[4] Los Angeles PT-141/Bremelanotide for Men | Beverly Hills PT 141 Nasal Spray
[5] The Top Benefits Of Bremelanotide For Men
[6] PT 141 Peptide Pros and Cons: Understanding Its Benefits And Risks
[7] How Long Does PT-141 Last? | Invigor Medical
[8] Reignite Your Passion: The PT-141 Experience for Men - Burick Center for Health and Wellness
[9] https://gamedaymenshealth.com/pt-141-peptide-therapy/

And you thought Viagra was expensive when it came out.
Interesting article on PT-141 here:
The Absolutely Amazing ED medicine Bremelanotide PT-141
You will need a second on your mortgage if your lady wants to try it out:
Amag’s female libido injectable therapy to sell at $899 | Physician's Weekly
Even discounted prices will require a second mortage:
https://www.goodrx.com/vyleesi
"Home Brewed" for a LOT less
 
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Get your first prescription for a $0 copay and pay no more than $99 for refills*

Vyleesi - Bremelanotide Injection - HSDD Prescription Treatment

Each patient’s eligibility is evaluated on an individual basis. In compliance with federal regulations, patients insured by a government-funded program (Medicaid, TRICARE, etc.) are not eligible. Patients must be 18 or older to qualify. These programs and any assistance provided may be discontinued or modified at any time based on eligibility, state and local laws, and program availability.


Financial assistance applies to the patient’s copay, coinsurance, or deductible for patients receiving Vyleesi. AMAG contributions against patient deductible and/or out-of-pocket maximums are subject to possible health plan restrictions. AMAG Pharmaceuticals will help lower the out-of-pocket cost to a $0 copay for the patient’s first prescription. AMAG will also provide copay assistance to lower the out of pocket cost for refills to a maximum copay of $99 per 4-pack. AMAG copay assistance will only apply to 2 fills every 30 days. Enrollment into the program cannot be retroactive
 
The devil is in the details. Does it say anywhere what income cap is when you go into second mortgage level:)
Also if you are one of the folks that are here "In compliance with federal regulations, patients insured by a government-funded program (Medicaid, TRICARE, etc.) are not eligible" you are screwed:) Also TRICARE, read Active duty military and retired military.
 
I wonder if this is the NEW FDAs policy... Don't care if it works as long as some company makes a fortune selling it.... Or is that the old policy also?
 
I just worked my way through one vial and never had much problem with any nausea. I felt it but it was mild, and got less with every dosing. Just my 2c.

i worked up to 2 mg. Effects included random boners that became annoying and even a bit concerning, and being interested in every woman in sight.

I paid £23 on ebay for my first batch, and have gone to Alibaba for the next, meaning it will be $80 shipped for 10 10mg vials. Taking 2mg once or twice per week means that the $80 will last me 6 months and beyond. I guess many would find this route too risky.

If you are just starting to see signs of ED but can still perform unaided, the addition of cialis, cabergoline and 2mg pt 141 may just let you perform better than ever at 47 or beyond. That is what has happened for me. It does mean you'll need to find someone with a certain level of appetite to enjoy it with you.
 
You can get this through compounding pharmacy‘s .

My doctor prescribes it to me and it’s much more reasonably priced I get it from a compounding pharmacy in Kentucky. No need to buy the prescription.. it’s like Cialis just buy it from a compounding pharmacy
 
Given my 2 decade battle w/ no libido and horrible ED, I just ordered some of this.

Any updated experiences? Should only use 2x per month. Usage after 1st time wasn't as good. Suggest taking prior to meeting a girl for a drink and maybe good to go? Worth trying once on my own to see how it works?

It takes a few hours to kick in?
 
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I found it very helpful and can tolerate the 2 mg dose with very little side effects very slight nausea for the first 20 minutes which gets better every time you use it. It’s got a half-life of around three hours but it seems to last 24 hours for me. If 2 mg is an enough you can work your way up some of the studies went up to 4 to 6 mg.

Dr. should be able to order it tailor-made pharmacy in Kentucky. I’ve used it several days in a row with no problems apparently if you use too much you can get hyper pigmentation on your skin blotchy spots it does give me a pretty big flash makes me look like I just got done tanning. Wife likes it lol
 
I found it very helpful and can tolerate the 2 mg dose with very little side effects very slight nausea for the first 20 minutes which gets better every time you use it. It’s got a half-life of around three hours but it seems to last 24 hours for me. If 2 mg is an enough you can work your way up some of the studies went up to 4 to 6 mg.

Dr. should be able to order it tailor-made pharmacy in Kentucky. I’ve used it several days in a row with no problems apparently if you use too much you can get hyper pigmentation on your skin blotchy spots it does give me a pretty big flash makes me look like I just got done tanning. Wife likes it lol

PT-141 affects pigment? I thought that was the Melanotan?

Do you still take it? Did it's efficacy wear off or did it always work the same?

I bought this - 10mg vial. Buy PT-141 Peptide | Nootropic Source

How much bacteriostatic water do I reconstitute a 10mg vial with?
 
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Yes they have a warning that says if you taken more than eight times in a month it can cause some pigment change ... I haven’t seen anything but it does make you look wonderfully tan after you take it .

So far for me it hasn’t lost any of its efficacy and I don’t reconstitute it comes premade for me from tailor maid pharmacy in Kentucky in a 10mg vial.
 
PT-141 affects pigment? I thought that was the Melanotan?

Do you still take it? Did it's efficacy wear off or did it always work the same?

I bought this - 10mg vial. Buy PT-141 Peptide | Nootropic Source

How much bacteriostatic water do I reconstitute a 10mg vial with?

Advice I've seen suggests 1ml. I haven't seen any tanning effect after a few doses.

Now I have received my Alibaba consignment, I can report back. First observation, there is more powder in the vial than the Europe sourced stuff. Second, it dilutes to a slightly opaque looking liquid, where the other stuff was clear. I first tried 0.2 mg as a test dose, all good after a few hours, so took 2 mg before bed. I think it was definitely stronger. Woke up with a boner that took a good hour to go away. Next time I will skip the 5mg cialis because it was a bit much. I am hoping I can get more of the aphrodisiac effect I've heard about instead of just the boner. The effect was there, but mild. Probably skip cialis and try 3mg next time.

This is the stuff I got, came in 2 weeks.

Pharmaceutical Grade Peptides Bremelanotide Pt 141 - Buy Pt 141,Bremelanotide Pt 141,Peptides Pt 141 Product on Alibaba.com
 
I was told with HCG the amount of powder is changed with how much air is in the powder. HCG from APS looked like half as much as Empower HCG. The amount is the same it just looks like there is more in it.
 
Advice I've seen suggests 1ml. I haven't seen any tanning effect after a few doses.

Now I have received my Alibaba consignment, I can report back. First observation, there is more powder in the vial than the Europe sourced stuff. Second, it dilutes to a slightly opaque looking liquid, where the other stuff was clear. I first tried 0.2 mg as a test dose, all good after a few hours, so took 2 mg before bed. I think it was definitely stronger. Woke up with a boner that took a good hour to go away. Next time I will skip the 5mg cialis because it was a bit much. I am hoping I can get more of the aphrodisiac effect I've heard about instead of just the boner. The effect was there, but mild. Probably skip cialis and try 3mg next time.

This is the stuff I got, came in 2 weeks.

Pharmaceutical Grade Peptides Bremelanotide Pt 141 - Buy Pt 141,Bremelanotide Pt 141,Peptides Pt 141 Product on Alibaba.com

I got mine from here: Nootrpic Source

Do you only take before bedtime? Being single, I'd want to try taking it at 8:00pm and go to the bar.
 
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K keep me posted please. Is 3mg a lot? how often are you taking - there is risk of desensitization.

Well, I am no expert, so only have my experience and accounts of others

3 mg would be way too much for a first dose. I am doing my 5th or 6th experiment spread over 3 months. Last 3 were 2mg, and I have seen reports that some people end up on a higher dose.

Like any tolerance build up, I would expect it to reset over time. At least I haven't heard anything about permanent tolerance. It's been around quite a while now.
 
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