The ‘abortion pill’ may treat dozens of diseases

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Apart from its two FDA-approved uses, mifepristone is also being investigated in clinical trials for breast cancer, brain cancer, prostate cancer, alcoholism, post-traumatic stress disorder and depression, among other conditions.

Dr. Rita Nanda, the director of breast oncology at the University of Chicago, is running several breast cancer clinical trials looking at the effects of mifepristone and combined with chemotherapy. Previous research has shown chemotherapy doesn’t work as well for patients with active glucocorticoid receptors in their breast cancer tumors, Nanda said.

“By blocking the glucocorticoid receptor with mifepristone, we hope to enhance the effectiveness of chemotherapy,” she said. She’s also in the early stages of trying to determine whether this strategy works for ovarian cancer and prostate cancer.

 
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