Testosterone Products in Canada - (oral TU, transdermal, injectables)

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madman

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Big pharma transdermal T patch Androderm manufactured by Allergan Inc. was discontinued back in 2018!

Big pharma brand name Andriol (oral TU) manufactured by Merck was also discontinued back in 2018 and more recently 2024 our beloved Delatestryl (testosterone enanthate) manufactured by Valeant has been discontinued.

The only oral TU available is the generic PMS-Testosterone and Taro-Testosterone capsules.

Come 2025 we may have the option to use the newer versions of oral TU Kyzatrex or Tlando which are available in the US as Marius Pharmaceuticals and Verity Pharmaceuticals are currently seeking approval from Health Canada!

The only injectable TE available is the recently approved generic Hikma testosterone enanthate although it looks as though there is going to be an ongoing shortage in the market!

For injectable TC we still have big pharma Depo-Testosterone manufactured by Pfizer or generic Taro-Testosterone Cypionate.

Main downfall here is they are both only available in the 100 mg/mL strength!

When it comes to transdermal T we still have big pharma Androgel manufactured by BGP Pharma ULC and the generic Taro-Testosterone gel or brand Testim gel manufactured by Paladin Labs Inc.

Downfall here is the strengths are low compared to compounded transdermal gels/creams.

Luckily we still have the option of seeking out compounded transdermal or injectable T.

We also still have nasal T gel Natesto manufactured by Acerus Biopharma Inc but they are on shaky ground!

Sorry bros but the short-acting injectable TP (testosterone propionate) will never be available so your only option would be seeking out a UGL source!




Screenshot (40200).png








 
Defy Medical TRT clinic doctor
 
Big pharma transdermal T patch Androderm manufactured by Allergan Inc. was discontinued back in 2018!

Big pharma brand name Andriol (oral TU) manufactured by Merck was also discontinued back in 2018 and more recently 2024 our beloved Delatestryl (testosterone enanthate) manufactured by Valeant has been discontinued.

The only oral TU available is the generic PMS-Testosterone and Taro-Testosterone capsules.

Come 2025 we may have the option to use the newer versions of oral TU Kyzatrex or Tlando which are available in the US as Marius Pharmaceuticals and Verity Pharmaceuticals are currently seeking approval from Health Canada!

The only injectable TE available is the recently approved generic Hikma testosterone enanthate although it looks as though there is going to be an ongoing shortage in the market!

For injectable TC we still have big pharma Depo-Testosterone manufactured by Pfizer or generic Taro-Testosterone Cypionate.

Main downfall here is they are both only available in the 100 mg/mL strength!

When it comes to transdermal T we still have big pharma Androgel manufactured by BGP Pharma ULC and the generic Taro-Testosterone gel or brand Testim gel manufactured by Paladin Labs Inc.

Downfall here is the strengths are low compared to compounded transdermal gels/creams.

Luckily we still have the option of seeking out compounded transdermal or injectable T.

We also still have nasal T gel Natesto manufactured by Acerus Biopharma Inc but they are on shaky ground!

Sorry bros but the short-acting injectable TP (testosterone propionate) will never be available so your only option would be seeking out a UGL source!




View attachment 48145











00:29:13 - Oral vs Injectable Testosterone: Benefits and Comparisons

01:05:55 - Kyzatrex: A New Approach to Testosterone Delivery





If your goal is to minimize chances of driving up hematocrit let alone hitting a high-end short-lived daily peak twice daily then 400 mg BID is most likely the way to achieve such unless you are one of those hyper responders who will fare well on a lower daily dose!



*At a mean follow up time of 6 months, patients demonstrated a significant increase in TT (263 to 798 ng/dL), drop in SHBG (32.4 to 17.83 nmol/L), and increase in calculated fT (7.24 to 26.74 ng/dL). FSH and LH, while lower, were maintained at non-zero levels (FSH from 5.7 to 2.9 mIU/mL and LH from 3.3 to 1.9 mIU/mL). Estradiol modestly increased (20.5 to 24.7 pg/mL) while hematocrit did not significantly increase (44.9% to 47.4%). No patients reported testicular atrophy or were initiated on aromatase inhibitors. One patient had a hematocrit rise above 52% (53.2%) and was reduced to 300 mg BID.

* Initiating oral TU therapy with Kyzatrex at 400 mg BID is safe and effective in achieving therapeutic serum testosterone levels. The high dose was well-tolerated and resulted in substantial symptom improvement, high patient satisfaction, and adherence. These findings support considering a higher starting dose for hypogonadal men considering oral TU therapy.





 
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