Testosterone Cypionate and BPH - advice needed

[aneuman]

like someone else said 80mg is lowish dose so you might not get any neg sides and you may feel better eg less anxious, you could always try it , I am on 30mg Cyp and 70 Androgel, none of the probs you mentioned except BPH but its the DHT from the Androgel causing BPH mainly

Good to know, thanks for opining. I thought about Androgel as well but I've heard about the DHT and BPH and decided against it.

How do you manage your symptoms? Any reason why not taking a high T-Cyp dose and drop or reduce the gel to improve the BPH?

Thanks

 

[aneuman]

I read the portion of the study attached. I would like to see the entire article, but have not had the luck to get to it via my phone screen.
What dosage/ frequency did the use?
I will try to get the study via laptop later, just asking it it was there and I couldn't find it.

I asked ChatGPT about this and this is what it said:

There is some evidence to suggest that low-dose human chorionic gonadotropin (HCG) may have potential benefits for managing symptoms of benign prostatic hyperplasia (BPH), a condition in which the prostate gland enlarges and causes urinary symptoms. HCG is a hormone that is naturally produced in the body during pregnancy, but it can also stimulate the testes to produce testosterone and other hormones in men.

One study published in the Journal of Clinical Endocrinology and Metabolism in 2005 looked at the use of low-dose HCG (500 IU three times per week) in men with BPH who were not candidates for surgery. After six months of treatment, the men experienced significant improvements in their urinary symptoms, as well as increases in their prostate-specific antigen (PSA) levels and serum testosterone levels. The authors of the study suggested that the HCG treatment may have helped to shrink the prostate gland, improve bladder function, and reduce inflammation.

Another study published in the Journal of Andrology in 2012 evaluated the use of HCG as an alternative to standard medical therapies for BPH, such as alpha-blockers and 5-alpha reductase inhibitors. The study found that HCG treatment (500 IU every other day for 12 weeks) resulted in significant improvements in urinary symptoms and flow rates, as well as reductions in prostate volume and PSA levels.

While the use of low-dose HCG for BPH is not yet widely accepted as a standard treatment, these studies suggest that it may have potential benefits for some men. However, more research is needed to fully understand the risks and benefits of this approach, as well as the optimal dosing and duration of treatment. Men considering HCG treatment for BPH should discuss the potential risks and benefits with their healthcare provider.

But let's take this with a grain of salt and ChatGPT is prone to hallucinations and I could not find a link to any of the studies above. However, if it made it up, it chose 500 IU 3 times weekly in both cases.

 

[Willyt]

You may be right, maybe I should not pursuit 700 or 800, but 500-600 would make me feel better. Would it be possible to get this number with T-Cyp, maybe 60 mg a week or something like that?

Try the much heralded 10mg daily (cypionate or enanthate). Only 70mg per week, but my guess is that you will exceed TT of 700. You have same SHBG as me and I only use 7-8mg daily. There are number of us dosing in 50-60mg weekly range.

But even at low dose TRT may aggregate your BPH. Only one way to find out...

 

[aneuman]

Try the much heralded 10mg daily (cypionate or enanthate). Only 70mg per week, but my guess is that you will exceed TT of 700. You have same SHBG as me and I only use 7-8mg daily. There are number of us dosing in 50-60mg weekly range.

But even at low dose TRT may aggregate your BPH. Only one way to find out...

Thanks for the advice, and totally understand about BPH. It's a bitch, and you never know what exacerbates it.

One question, have you tried weekly protocol, or twice a week as opposed to daily? any negative results? I would very much rather avoid pinning every day, if possible.

I would be happy to join the 50-60mg weekly range. Even though naturally I tend to be kind of "the more the better", I understand that's not necessarily the case in most situations.

One question, under this protocol of 10mg daily (equivalent to 35mg every 3.5 days) you get about 700 ng/dL TT? What about your Free T, SHGB, E2?

What benefits have you said you've derived from TRT at your current level? Mood? Libido? Arousal? Body composition?

I really appreciate your take on this. I was thinking about 80 mg/week but now that you mention 50-60 is possible I'm leaning more towards it. I'd like to hear you comments on my questions above.

Thanks again.

 

[Willyt]

Thanks for the advice, and totally understand about BPH. It's a bitch, and you never know what exacerbates it.

One question, have you tried weekly protocol, or twice a week as opposed to daily? any negative results? I would very much rather avoid pinning every day, if possible.

I would be happy to join the 50-60mg weekly range. Even though naturally I tend to be kind of "the more the better", I understand that's not necessarily the case in most situations.

One question, under this protocol of 10mg daily (equivalent to 35mg every 3.5 days) you get about 700 ng/dL TT? What about your Free T, SHGB, E2?

What benefits have you said you've derived from TRT at your current level? Mood? Libido? Arousal? Body composition?

I really appreciate your take on this. I was thinking about 80 mg/week but now that you mention 50-60 is possible I'm leaning more towards it. I'd like to hear you comments on my questions above.

Thanks again.

Most daily guys including myself have tried 1x or 2x per week and did not like it due to the swings. However, there are several popular threads about guys preferring less frequent injections. Its just personal preference and how your body responds.

You've clearly done your homework and probably realize now that there is no perfect protocol. It's all a trade-off based on what you prioritize (e.g., athletic performance, sleep, mood, energy, libido, etc.). I try to focus on balanced approach.

Here are my latest results on Enan/Prop blend of 8mg

Test results for 8mg daily blend (Enan + Prop)

Inspired by @Cataceous, I have been tinkering with Enan/Prop blends for the past year. The idea behind the daily blend is to re-introduce daily T fluctuation. Inject first thing in morning to peak early in day and let levels come down overnight. For example, Cat’s personal data based on 4:3...

www.excelmale.com

Here is good thread on low dose

Less than 50 mg of T per week

Do you inject less than 50 mg of T per week? If so, how do you feel? What were/is your lab results before/after you started TRT? I am on 60 mg with high FT, T and E2. I am considering 50 mg, or even less. I'm on Enathate.

www.excelmale.com

 

[Keepfit1]

Good to know, thanks for opining. I thought about Androgel as well but I've heard about the DHT and BPH and decided against it.

How do you manage your symptoms? Any reason why not taking a high T-Cyp dose and drop or reduce the gel to improve the BPH?

Thanks

I manage BPH by getting Rezum steam treatment about 18 months ago, I tried full dose Cyp and no gel but felt hypogonadal, posted on here about this before and spoke to many experts, its just a minority on here that need some gel so dont worry about it , it prob wont be a issue for you

 

[aneuman]

Most daily guys including myself have tried 1x or 2x per week and did not like it due to the swings. However, there are several popular threads about guys preferring less frequent injections. Its just personal preference and how your body responds.

Thanks a lot. I read you posts in the threads mentioned and have learned a lot from it. Thanks a lot.

My biggest concern is NOT the numbers, but the subjective feelings, with a big emphasis in preventing high hematocrits/hemoglobin, high blood pressure, and prostate/BPH symptoms.

I've had great numbers (as seen in my original posts) but the subjective feelings have never been great. Recently, I've started driving what appears to be great results from HCG in prostate-related issues, particularly Ian and urinary flow. I'm pretty sure is due to HCG as I skipped it one day while still taking Enclomiphene and the problems returned, next time, I took 250 IU HCG and skipped EC and the symptoms improved.

You've clearly done your homework and probably realize now that there is no perfect protocol. It's all a trade-off based on what you prioritize (e.g., athletic performance, sleep, mood, energy, libido, etc.). I try to focus on balanced approach.

Thanks, yes, I've been reading about it for many years, but I've found several problems, that this forum and people like you help me solve:

• Doctors:
  • not always up to date, sometimes not willing to even prescribe testosterone or treat hypogonadism symptoms
  • Prescribing Testosterone Cypionate, HCG, enclomiohene, clomid, or anything you want in a nonchalant way, without even hearing the symptoms, essentially drug dealers
• Research/Studies: In many cases, research focuses too much in raising testosterone, without stating whether the symptoms were resolved, or what symptoms were resolved, so you end up with statements like "This study shows testosterone cypionate is effective in raising testosterone levels in hypogonadal men"
• Forums: many of them packed with bro science, contradictory anecdotes, one size fits all answers, n=1 generalizations, etc.

If I went to put on a scale the order of preference in which I want to get improvement:

1. Arousal/Libido
2. Mood
3. Sleep
4. athletic performance

But I know, from the great mid 20th century British philosopher Mick Jagger, that "You can't always get what you want. But if you try sometimes, well, you might find you get what you need"

Thanks again @Willyt for your help.

 

[aneuman]

I manage BPH by getting Rezum steam treatment about 18 months ago, I tried full dose Cyp and no gel but felt hypogonadal, posted on here about this before and spoke to many experts, its just a minority on here that need some gel so dont worry about it , it prob wont be a issue for you

Interesting, would you care commenting on that procedure? Experience, results, are you happy with it? Covered by insurance?

Thanks for your comments. Appreciated.

 

[Keepfit1]

Interesting, would you care commenting on that procedure? Experience, results, are you happy with it? Covered by insurance?

Thanks for your comments. Appreciated.

Best to google it, no long term probs, no impotence or retro ejac, day patient procedure , catheter for a week which is unpleasant, no bike riding 6 weeks, urine volume about double what I was pre op but it was bad pre op, it’s the least invasive op for BPH