SteveCleves
Well-Known Member
Just as another data point I found this todayThats one mechanism why telmisartan has neuroprotective effects, because it increases prolactin and lowers dopamine. This is totally turn off for me. Because i personally would rather increase dopamine and lower prolactin.
Association between Serum Prolactin Levels and Neurodegenerative Diseases: Systematic Review and Meta-Analysis
Abstract. Introduction: Prolactin (PRL) exerts inflammatory and anti-inflammatory properties and is also thought to play an important role in the pathogenesis of neurodegenerative diseases (NDs). However, serum PRL levels in patients with NDs were inconsistent in the research literature...
www.karger.com
"Conclusions: Our meta-analysis showed serum PRL levels in patients with HD and MS were significantly higher than those in healthy controls. Serum PRL levels were associated with age, region, and detection method. Other larger sample studies using more uniform detection methods are necessary to confirm our results."
And this gem:
The role of prolactin in central nervous system inflammation
Prolactin has been shown to favor both the activation and suppression of the microglia and astrocytes, as well as the release of inflammatory and anti-inflammatory cytokines. Prolactin has also been associated with neuronal damage in diseases such as multiple sclerosis, epilepsy, and in...
www.degruyter.com
"PRL possibly exerts a dual activity on inflammation; it either inhibits or promotes this type of immune response." lol...way to take a stand!
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