I can actually feel the cream kick in. I like the way it feels applying prior to my workouts. I can't imagine dosing before bed.Can I wake this thread back up and get some feedback? Who is using cream out there? Tim L, the OP indicated he applies cream only at night. I am considering this, but have not seen anyone else state they are doing this and Tim L disappeared.
As of now, I apply cream in the AM only, but notice a surge of energy in mid to late afternoon, about 8 hours after application (don't know why, as free T is supposed to peak about 2 hours after application. Maybe it's the result of a downstream conversion? E2? DHT?). In any case, based on this, I have considered doing what the OP does and applying at night before bed to scrotum only. Tim L, if you are out there, are you still doing this? Is anyone else doing this, or have you tried it in the past?
I have bioidentical testosterone cream of 30Mg each dose. Passing this cream on the testicles is a very strong dose? I never used it on the testicle and I have doubts about the increase in DHT and PSA. ThankI use Testavan 1 pump on the scrotum and lately had my tt and ft checked and the result was higher then max for both . I now returned to applying to my shoulders and just a tiny amount on my balls . In a month I will check again.
Thank you Fortunate. My cream is based on pentravan. My intention is to apply it to the testicles just to increase DHT and libido a little and keep the TRT Protocol of 25 mg of cypionate 3x a week. ThankI have been posting on an off about cream. About two months ago, I started with 50mg to scrotum, 50mg to shoulder in AM and another 50mg to shoulder in PM. Felt great initially, but started to have an ”over the top feeling” on that, so I started to back off.
I played with various strength creams (150 and 200) at various locations in various combinations. I came to a few conclusions:
I have not gotten bloodwork after using cream, but I suspect that even at low doses, I was probably uncomfortably supraphysiologic
- I seemed to reach a max concentration of something (T or DHT) about 8-10 hours after a morning application
- This confused me, as I thought max concentration was around 2 hours later. But, there is a pharmacokinetic article published in 2017 in the journal Andrology that everyone tends to cite when discussing scrotal absorption. The article actually quotes another study that has shown peak T concentrations can be 6-16 hours after application when applied to non-scrotal skin
- This may explain why I felt the effects of the cream in the late afternoon/early evening
- After the initial honeymoon, I got to a point when even small doses gave me an “over the top” feeling late in the day (rapid heart rate, a touch of a head rush, etc.)
To Gerardo’s question, scrotal application has very high absorption rates compared to the arms, so I would be careful. Pay attention to your symptoms and get bloodwork after starting your protocol. In my case, I was using 50mg on the scrotum and another 50 on the shoulder and it felt like it was too much. 30mg doesn’t seem unreasonable, but I know nothing about the product or the base it’s in.
For myself, I would not rule out trying some lower dose, maybe on the shoulder only. But, for now, it’s back to Natesto for me (gentle, easy, quick and easy to stop if I want to try something else).
Post back here and let us know how it goes.Thank you Fortunate. My cream is based on pentravan. My intention is to apply it to the testicles just to increase DHT and libido a little and keep the TRT Protocol of 25 mg of cypionate 3x a week. Thank
I haven't used testosterone cream yet. I'm waiting for my TRT protocol to stabilize.Post back here and let us know how it goes.
I have been posting on an off about cream and Natesto. Still experimenting and if I reach a definitive conclusion, I will post feedback here. That said, one of the things I have concluded thus far is that I think I have the opposite problem many people notice with cream. Instead of not getting enough hormone, I sense I am getting too much. At doses similar to what many here describe using, I feel "over the top", nervous and anxious with cream. The other odd thing I've noticed is that I don't feel the subjective hormone effects until 8+ hours after application.
I know that commercial topicals (androgel, etc.) tend to get vilified here, but I wonder if the lower dose would be better for me. I currently have compounded topical hydrogel on order. The thinking is that I don't want more absorption. But, I wonder if it would be more rapid, rather than the 8 hour delay I feel now. If it works more quickly, I can just reduce the amount until I find the right dose.
Long prelude to my question: anyone here use Testim, Androgel or one of the other commercial products? If so, has it worked long term for you? I also posted a poll on this question here.
Tried low dose on shoulders. Around 75mg at a time. Had trouble with it. Never tried abdomen.Have you been playing with lower dosages and applying on the abdomen rather than the scrotum?
That seems to do the trick for me, I'm feeling less anxious and lot more euphoric.
Can you elaborate on "trouble with it"? Low absorption? What were your levels on shoulders only?Tried low dose on shoulders. Around 75mg at a time. Had trouble with it. Never tried abdomen.
Opposite problem. Anxiety, palpitations, etc. felt way over the top.Can you elaborate on "trouble with it"? Low absorption? What were your levels on shoulders only?
Over the last several years, I have been on it more than other forms of TRT. My impression is the same:@Fortunate Any new impressions regarding Natesto?
I have a few follow-up questions: what dose are you using? What do you think accounts for the improved experience? Have you tried a similar dose on the shoulders? If so, how is your current protocol better than applying to the shoulders?Have you been playing with lower dosages and applying on the abdomen rather than the scrotum?
That seems to do the trick for me, I'm feeling less anxious and lot more euphoric.