Struggling with bloodwork consistency. TRT bloodwork included.

Started TRT through a clinic and I didn’t have much if any guidance on dose. Was put on 200mg Test Cyp a week and .5mg Arimidex 2x a week. I followed this for about 2 years. Bloodwork numbers were hard to follow because each doctor through the clinic basically just said “everything looks good” but when I looked at my numbers nothing looked good. I felt like starting at 200mg a week was high but found this was the dose all their patients get regardless. (Probably a bad sign). I ultimately dropped down to 160mg.

I decided paying the clinic so much wasn’t worth it so I consulted with my primary doctor who suggested I go through him as my insurance covered it. He’s not an expert but willing to listen to my concerns and work with me to be optimal for how I should be feeling as well as being safe.

Note: I feel like that I definitely convert more to estrogen and have suffered the side effects more so than others.

Current TRT protocol:

-140mg a week of Test Cyp. Single IM dose on Mondays.
-1mg Arimidex on Mondays. 1mg Arimidex or Thursday.
-No processed foods. Low carbohydrate with high fat and moderate protein from meat. High water intake. 7-8 hours of quality sleep every night.
-Blood donations as needed to maintain RBC, hematacrit, etc. Was doing double reds every 6months but switches to full donations as I can do them more often.


Bloodwork timing question: I can’t seem to get my timing right as far as when I should get my blood test.

Bloodwork timing as of the last blood test: TRT injection (140mg) on Monday early morning. Bloodwork test on Thursday early morning.



I was doing 2x a week of a split dose but injections so often was annoying. I do understand it might help level my numbers better and help with estradiol.
 

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I have low SHBG and I like my E2 number to mirror my SHBG value. You stated E symptoms and you're still bothered by whatever you're feeling so push it a little lower. I don't think your numbers or dosing is otherwise troubling, keep it simple and just push your E2 a little lower. Ideally you want to time your bloods on Monday morning for your trough and then do your injection, since you're injecting once per week.
 
I would inject 50 mg of testosterone twice a week. And that's it, no ai. See how you feel in about 12 weeks. Also, I would donate blood at least once to keep your HCT in range
 
I would inject 50 mg of testosterone twice a week. And that's it, no ai. See how you feel in about 12 weeks. Also, I would donate blood at least once to keep your HCT in range
I was thinking I could lower it and be able to drop AI. When do you suggest the bloodwork to be done as far as injection schedule
 
The AI can deceive you into thinking your estrogen is fine, when in reality, serum E2 means very little. Estrogen is converted, made in tissues (50 x higher than serum levels) which can't be measured and this it's where estrogen exerts its effects and you're blocking estrogen inside the tissues.

You can have a magneesium, or potassium deficiency and still have normal serum levels. The tissues is where the magic happens.

Also, depending on the location in the body, the brain converts estrogen at a higher rate than other areas of the body, yet you're blocking estrogen eveningly through the body.
 

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