Nelson Vergel
Founder, ExcelMale.com
Association between Gut Microbiota and Body Composition in Japanese General Population: A Focus on Gut Microbiota and Skeletal Muscle
This study aimed to investigate the gut microbial genera associated with skeletal muscle mass, using a large-scale survey from the standpoint of preventing sarcopenia. A total of 848 participants were included in the analysis. The mean (SD) ages of men ...
www.ncbi.nlm.nih.gov
"Our study with participants of a large-scale health check-up revealed that Blautia and Bifidobacterium were positively correlated with appendicular skeletal muscle mass ASM/body weight BW only in men. In addition, Eisenbergiella was positively correlated with ASM/BW only in women. The relationship of ASM/BW with Blautia, Bifidobacterium and Eisenbergiella has not been shown in previous studies. These gut microbial genera may help increase skeletal muscle mass. ASM/BW may clarify the relationship between gut microbiota and skeletal muscle mass without being affected by overweight or body fat mass, even in individuals with obesity or excess body fat mass."
"The gut microbial genera and composition associated with ASM/BW differed between men and women [47,48], and sex hormones are considered major determinants of the composition of the gut microbiota [49]. Sex hormones also contribute to differences in muscle synthesis and fat distribution between men and women [50]. The sex difference in the association between gut microbial genera and ASM/BW might be explained by adjusting for confounders, such as sex hormones."