Interesting discussion. This is one of my original labs after starting with Dr. Saya on 160mg test per week a few years ago, along with .15mg anastrozole 2x per week.
My estrogen was high, my nipples felt itchy, I previously had gyno surgery at 18 from puberty (safe to say high converter) & was concerned it was about to be deja vu.
After we adjusted my anastrozole to .25mg 3x week and got it down to around 30, I felt much better subjectively, and the symptoms I had were resolved.
Medicine & treatment, like most things in life, usually shouldn't have blanket statements attached to them. To say I shouldn't have been treated to reduce my E2 levels because there are no studies to show the benefit seems pretty ridiculous. I think everyone would agree TRT is pretty much in it's infancy in terms of available information from published studies to match the current understanding among specialists. Much of what we have is outdated and poorly executed.
My $.02
Curious to hear if Dr. Nichols would still have an issue prescribing an AI to someone with my background, symptoms, and numbers?