madman
Super Moderator
Does diurnal effect even apply to guys on TRT?
I mean your natural T production is shutdown. All T comes from a needle the only rhythm is how frequest you inject.
The closest one could get to mimicking the natural diurnal rhythm of testosterone of a healthy young male is using the testosterone patch or transdermal (when only applied once daily) and even than most would need double the dose when using patches or higher doses of transdermal to attain high/normal physiological testosterone levels. As far as injections they cause steady state and in no way mimic the natural diurnal rhythm albeit injecting daily would result in the most consistent levels although still steady state.