results from new protocol

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RickB

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I was taking 200mg cypionate a week with 6.25mg exemestane twice a week for quite a while and had good numbers on paper. They were a little high for madman's way of thinking, but nothing crazy. Symptoms wise I wasn't getting all that much out of trt and was eating a lot.

I then stopped trt for a 35 days and restarted with a protocol of 100mg cypionate every 5 days, no AI.

After 50 days on this protocol, 19.5 hours before absolute trough, my results are:

Total 974 ng/dL (193-740)
SHBG 33.5 nmol/L (19.3-76.4)
Albumin 4.9 g/dL (3.5-5.2)
Estradiol 36.6 pg/mL (11.3-43.2)

According to the method they used, my calculated free is 213.7 pg/mL (38.7-147). According to formula I used my free is 21.4 ng/dL, which from previous experience would probably be my free T direct if they'd done that assay (which they usually do).

So these results are pretty good on paper. They're a little premature of course, and I'm seeing the doctor on Aug 2 and will get tested again. Symptom wise I'm less hungry than I'd been on previous protocols and have more energy, but I have zero sex drive. Try to masturbate and barely get up to half mast. That area was better with my previous protocol, but my life circumstances were much different and could account for a lot. Regardless, under neither protocol was I even getting morning wood (unless it was cold) and never got waking erections without foreplay or extreme concentration.

I probably won't change protocols at all if my results are similar on Aug 2, as I think these sex issues are almost certainly down to something other than androgens. But is there anything that stands out about these results to suggest they're not as good as they seem? I think madman will say I'm still taking too much. Anyone else have any ideas?
 
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I woke up today (day 55) with with morning wood despite warm temperature in room, so maybe this protocol holds some promise.
 
To me your numbers look excellent. Have you ever tried not using AI or exemestane. You may feel better with higher E2.
 
To me your numbers look excellent. Have you ever tried not using AI or exemestane. You may feel better with higher E2.
Other than when I first started trt four years ago, this is my first time with no AI. They are no longer an option due to terrible elbow tendonitis which did not go away until I stopped taking them.

Not sure if I'm getting anywhere sexually on this protocol, but this morning was a good sign. I've had my estradiol this high before even on AI's, but I do believe the lack of an AI might have a positive affect beyond what's directly reflected on an E2 blood test.
 
Your through still seems little too high considering it's still pretty infrequent injection schedule, why not give lower numbers a go...
 
Your through still seems little too high considering it's still pretty infrequent injection schedule, why not give lower numbers a go...
As a matter of fact the last couple days I've found myself overeating again, which may not be related at all but is something I've wrestled with since starting trt. I'm going to cut back to either e6d or e7d.
 
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As a matter of fact the last couple days I've found myself overeating again, which may not be related at all but is something I've wrestled with since starting trt. I'm going to cut back to either e6d or e7d.
exogenous testosterone seems to have interaction with ghrelin, not sure if direct or not
 
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