Question about estradiol

[brunoreus]

The results are close enough that you can probably get by using only the non-sensitive test in the future.

Question, Is 33pg/ml (ROCHE ECLIA) a decent number for estradiol if I could raise free T? (10pg/ml)
And also, what do you guys think is the normal range for free T? Cause I keep reading different ranges?
Sorry for bothering with so many questions haha!

 

[Cataceous]

Question, Is 33pg/ml a decent number for estradiol if I could raise free T (10pg/ml)

Certainly 33 pg/mL is a "decent number for estradiol", depending on the circumstances.

Assuming your SHBG was 15 nMol/L at the time of the estradiol test, then calculated free estradiol is approximately 1 pg/mL, with a reference range of 0.2-1.5. So not very high in an absolute sense, but still possibly high relative to free T.

I assume you're using the direct free T test, which is inaccurate, and the reference ranges vary greatly between different labs. Do you have a measurement for total testosterone for your current protocol? As I mentioned in another thread, you really need total testosterone, total estradiol and SHBG to calculate decent estimates of the free hormones. Ideally the measurements are made at the same time.

In any case, raising testosterone implies a proportionate rise in estradiol, so the ratio won't change much. Assuming the ratio is actually a problem, it can be improved by reducing body fat or by using an aromatase inhibitor.

 

[slicktop]

Question, Is 33pg/ml (ROCHE ECLIA) a decent number for estradiol if I could raise free T? (10pg/ml)
And also, what do you guys think is the normal range for free T? Cause I keep reading different ranges?
Sorry for bothering with so many questions haha!

You've got to track your symptoms along with your numbers, or you'll end up chasing numbers forever. I don't think there's any two men on this forum that do everything 100% the same. An E2 of 33 could be fine for some of us, it could be terrible for others. Some of us want our E2 within a ratio of our testosterone, others go E2 to SHBG (which there is no published study to support, but two different PA's at Defy that I know of recommend that method and it's the one that works for me personally). Journal everything and let symptoms guide you. Numbers are ALWAYS secondary.