PSA numbers increasing on testosterone- Should I stop TRT?

[Drug350]

I'm glad that you got those results from TRT right from the start.
Especially libido. My over-all experience was really the opposite for the most part when it came to libido.
When I started T my PSA was .5 to .7. It is now hovering around 3.7. My Uro frowns on it but has cooperated till recently. I haven't pressed him as I had a couple of other problems going on unrelated to T.
Good luck with your trek.

Sorry to hear that. So far, every part of my life has improved. My sleep quality was absolutely terrible. For years I'd be taking some form of sleep aid (strictly over the counter) to try to fall asleep, and no matter what, I'd wake up repeatedly all night long, and feel exhausted getting out of bed. I just assumed it was my crazy hours with my on call job and getting older. Right from the first week on TRT my sleep changed. I could fall asleep within 5 minutes in bed and I wouldn't wake up until 8 hours latrr and I felt incredible. I am sleeping sooooooooo good now it's unbelievable. I never expected any sleep changes on TRT but mine has improved significantly. I'm also taking daily low dose Cialis and I find my bladder isn't bothering me at all. So maybe it's the Cialis. I'm going to change to twice weekly shots instead of weekly. I just got my numbers back and these are 7 days post shot, prior to taking my shot, and my numbers are higher than I'd have anticipated. These would be my lowest numbers for the week. I'm thinking immediately after my shot, I could be double these numbers. I'll have to get blood work done in the middle of my shots.

Total = 610 NGDL
Free = 11.8 NGDL
Bioavailable = 276.5 NGDL
SHBG = 40.0 nmol/m
Estradiol = 20 pg/ml

 

[broker]

Using testsosterone increases DHT which can enlarge the prostate. As your prostate enlarges, your psa rises with it. As we age, our prostate enlarges and psa gradually rises ( to a degree ). If your psa is normally 1.5 and after a year on trt it goes up to 2.2, that may warrant further testing.
fyi, your T numbers are great , why rock the boat.

 

[Drug350]

Using testsosterone increases DHT which can enlarge the prostate. As your prostate enlarges, your psa rises with it. As we age, our prostate enlarges and psa gradually rises ( to a degree ). If your psa is normally 1.5 and after a year on trt it goes up to 2.2, that may warrant further testing.
fyi, your T numbers are great , why rock the boat.

Well the only change I think I'm going to do is go to twice a week dosing instead of once weekly. I'll go 50 MG's, twice a week. My numbers at the end of the week look great with once a week dosing, but I'm thinking they may be too high in the beginning with that large 100 MG's dose. I'll give it a try after I see my Urologist next week and speak to her about it. I didn't realize that having sex, ejaculating, prior to a PSA test could effect it. Ignorance on my part. I'll abstain for 48 hours prior to my next PSA and see what it shows. Not sure how much the PSA change from .5 to 1.4 over 4 weeks was from starting TRT or having sex 3 times prior to having my blood draws and PSA tested. Maybe a combination of the two, I honestly don't know. I never knew sex could affect PSA numbers. Live and learn.