PSA changes

[Hammer]

Recently I discontinued taking Anastrozole (0.5mg/wk) since I lowered my testosterone dosage from 80 to 60 mg/week. My E2 has been running in the 20 - 25 range while total test levels were 950 - 1000. Since reducing my T dosage my last set of labs measured my TT at 750 and my E2 slightly above the range at 41(0 or <39). I feel good but my concern is that my PSA level that went from 0.8 to 1.4 ng/ml. I'm curious if the PSA increase is due to the discontinuation of the AI. Anyone have experience with this issue? Thanks Hammer!

 

[Vince]

Before I started trt my PSA was 0.9. after starting trt my PSA has held steady at 1.4 - 1.5. This has been for 5 years now. A reading of 1.4 should be of no concern. Your PSA reading will change from time to time, especially after working out or having sex.

 

[Hammer]

Before I started trt my PSA was 0.9. after starting trt my PSA has held steady at 1.4 - 1.5. This has been for 5 years now. A reading of 1.4 should be of no concern. Your PSA reading will change from time to time, especially after working out or having sex.

 

[Hammer]

Thanks Vince! Agreed, the PSA value itself is certainly within normal range for a 63 year old but the change from 1 to 1.4 in just a few months was surprising. I also read that NSAIDS can raise PSA which I was taking for knee pain prior to blood work.

 

[TorontoTRT]

NSAIDS lower PSA

 

[SilverSurfer]

Thanks Vince! Agreed, the PSA value itself is certainly within normal range for a 63 year old but the change from 1 to 1.4 in just a few months was surprising. I also read that NSAIDS can raise PSA which I was taking for knee pain prior to blood work.

retest in 6 months. I think you’re overreacting.