Progesterone in Men
- Thread starter Davet
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Nelson Vergel
Founder, ExcelMale.com
Progesterone Levels on TRT
I’ve seen various accounts of men on TRT with deficient levels of progesterone -- many of whom had normal levels prior to treatment. LH is important for leydig cholesterol -> pregnenolone conversion, and also for adrenal steroidogenesis. HPTA suppression and the subsequent absence of LH is...
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Nelson Vergel
Founder, ExcelMale.com
Started 50 mg per night of progesterone capsules from Empower 4 days ago (along with 100 mg of pregnenolone). I sleep deeper but I am super tired in the morning. The dose may be too high. I stopped it last night.
DixieWrecked
Well-Known Member
I know this is gonna sound crazy but you can try anal insertion. not sure if that's the correct terminology. Apparently this is a common way to do it for MTF transitioning. Except that is done with a much larger dose.
Don't these hormones work differently if taken orally?
Why did u go from 200mg to 100mg of pregnenolone?
And ya that dose might be too high. Not sure how much of the 50mg is getting absorbed when taken orally, but 1mg/ day of injectable prog brings my level to 0.4, and 2mg/ day brings my level to 1.6. Reference range is 0.0-0.5. All ng/ ml. And @Cataceous takes 0.6mg/ day of injectable prog and that brings his level to around 0.5-0.6 I believe. So depending on how much of the 50mg is actually getting absorbed it might be extreme overkill. Even if only 10% was getting absorbed that would be 5mg, which would have ur levels sky high I would imagine
Smokin Joe
Active Member
Since following the Progesterone/Pregnenolone threads I have tried both periodically over the last month.
The Progesterone certainly adds a better mental feeling with increased interest in morning to mid morning sex.
The Pregnenolone is one that I don't think that I can do.
The sleep is great but tbe day after I'm dragging and can't pull out of it. Even at 5mg its rough going.
It reminds me of tbe dhea feeling when I tried that.
Cannot do it.
So we'll see where the Progesterone takes me though I'm coming off T as my PSA has slipped up to 4.2 and my Uro will will stop my prescription until the fog clears. He's treating another immediate family member for Prostate cancer so I know whats coming.
All have a great Labor Day weekend!
The Progesterone certainly adds a better mental feeling with increased interest in morning to mid morning sex.
The Pregnenolone is one that I don't think that I can do.
The sleep is great but tbe day after I'm dragging and can't pull out of it. Even at 5mg its rough going.
It reminds me of tbe dhea feeling when I tried that.
Cannot do it.
So we'll see where the Progesterone takes me though I'm coming off T as my PSA has slipped up to 4.2 and my Uro will will stop my prescription until the fog clears. He's treating another immediate family member for Prostate cancer so I know whats coming.
All have a great Labor Day weekend!
Thanks for the anecdotes. So what form of progesterone are u taking, what dose, and what time of day are u taking it?
Smokin Joe
Active Member
Still using the NOW Brand until gone then a USP cream with no fillers.
10mg a half of pump at bedtime around 9:30.
10mg a half of pump at bedtime around 9:30.
On what part of the body are you applying the cream?
Smokin Joe
Active Member
I have applied it to both the Scrotum and the soft inner thigh close to my nuts. Rotation.
Nelson Vergel
Founder, ExcelMale.com
Physiological Role and Clinical Implications of Progesterone
Abstract The most recent studies of progesterone research provide remarkable insights into the physiological role and clinical importance of this hormone. Although the name progesterone itself means “promoting gestation”, this steroid hormone is far more than a gestational agent. Progesterone...
www.excelmale.com
That is a massive dose of progesterone for a male! I bet you could not even see straight!
Orally absorption is low. Around 7%. This is like taking around 3.5 mg in an injection. Which is still quite high. But not as high as one might think. Orally, 5-15 mg is a more physiological dose for men
Ya 3.5mg injected is definitely a very high dose like u said. 2mg/ day injected had my level at 1.6 (0.0-0.5)
Yes, this shows a very close trend with my progesterone injections. my injections of .6mg brought my level from .4 to .8 and .9 on two separate tests. At 24 hour trough.
I always injected before bed and tested in the morning, for reference
Do u still take the prog injections? What did u notice from it, good or bad?
Thank you! I was not aware of that! My wife takes 150mg every night and has been a lifesaver for her and sleep quality. She is 57 and great shape but really needs that!
I do not. I stopped that some time ago. I’ve recently experimented with oral progesterone pregnenolone and dhea. I’m still tinkering. Right now I’m on 2.5mg dhea 3x daily alongside my normal 250iu hcg. 5mg enanthate and 2mg of propionate. No progesterone currently. I’ve also added magnesium because I have high iron and low vit d. It just so happens magnesium deficiency is linked with both higher iron and low vit d!
Ya I’ve been huge on magnesium and it’s importance for years. I follow Morley robbins and Carolyn dean’s work on it. They’re the two biggest advocates of magnesium out there that I’ve found. If a person isn’t taking magnesium, the best advice I can give them is get on it asap! Thank me later
what benefits have you noticed from magnesium?
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