On the Sermorelin, when I tried it, it was cycled, and as I understood it, if it had worked for me, it would have been reduced amounts going forward but it didn't affect my IGF-1 at all.
In HIV studies, tesamorelin's (Egrifta is the brand name) effects on fat reduction and lean body mass increases reached a plateau after 26 weeks. Tesamorelin is very similar with Sermorelin.
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