JohnTaylorHK
Active Member
No Sir, in actual fact if you take exogenous T then endogenous T production is reduced, a double whammy for hypogonadism sufferers. Assuming you are doing a gluteal IM, then 50% of whatever quantity you inject will be metabolized within the specified half-life. After a further half-life period, another 50% (25% of the original amount) will be metabolized and so on. So the circulating T follows an exponential decline. Now if you add the same amount after the first half-life period, you will actually raise the circulating T again. Now you have 2 "components", both decaying at the same rate. If you graph this decline, you will see that it is NOT optimal, there is a greater opportunity to "smooth out" the associated peaks and troughs of the circulating T, ensuring a (more or less) steady level. The way to do this is to decide what circulating level you want, and then use 2 doses to achieve that. After the half-life lapses, use a single dose per half-life period. I have a spreadsheet which I created a few years ago, which may help someone. Sadly this forum will not allow me to upload it. PM me if you would like a copy. NamasteAre you saying therapy goes on too long like someone should stop after a certain amount of time because they would suddenly be making enough T on their own?