My testosterone dropped 50% in 2 months after starting Danazol and Thyroid

[jackjohnson]

Hi,
I went to a clinic and after my first blood test with a total T of 1116 and a very high SHGB, I started taking 50MG of Danazol every other day and Liothyronine/Levothyroxine 4.5MCG/19MCG daily, as well as Ipamorelin peptides. After 2 months I got tested again and my total T dropped in half to 547.

I had been doing more intermittent fasting, eat a lot of red meat, eggs, etc. My sleep hasn't been great, but it never is.

 

[Systemlord]

Danazol works by blocking the release of hormones.

 

[Nelson Vergel]

Danazol is an androgen without any of the androgen benefits. It shuts down your HPTA. Useless and worthless.

 

[jackjohnson]

Thanks for the reply. Why would they prescribe me this?

Based on my first set of labs, what would you have suggested?

 

[Nelson Vergel]

Did you miss saying you are on TRT? If you are, some doctors use it for decreasing SHBG. But if you are on TRT your total T should not have dropped. Please clarify.

 

[jackjohnson]

No, I went to the place to find out about it. They said since my Total was high that Danazol would remove SHGB.

 

[Nelson Vergel]

So, you are not on TRT. A Total T of 1116 ng/dL is your natural endogenous production.

By now you should know to stop Danazol. Don’t mess with your great natural T.

 

[tareload]

No, I went to the place to find out about it. They said since my Total was high that Danazol would remove SHGB.

Wow. Your SHBG was too high in the opinion of your medical provider and this person started you on danazol with TT over 1100 ng/dl? The goal was to reduce SHBG for what purpose given you aren't on exogenous Testosterone?

How did your provider explain your igf-1 before and after?

 

[jackjohnson]

So, you are not on TRT. A Total T of 1116 ng/dL is your natural endogenous production.

By now you should know to stop Danazol. Don’t mess with your great natural T.

Thanks, but isn't it all being negated by my really high SHGB? Is there something else you'd recommend?

 

[jackjohnson]

Wow. Your SHBG was too high in the opinion of your medical provider and this person started you on danazol with TT over 1100 ng/dl? The goal was to reduce SHBG for what purpose given you aren't on exogenous Testosterone?

How did your provider explain your igf-1 before and after?

Since my SHGB is so high, the high total was being negated. The though was that reducing SHGB via Danazol would increase my free T. He was very surprised when he saw this, and though the first test must have been a mistake. I don't recall about he igh-1 since I was focused on the other numbers being so strange.

 

[jackjohnson]

My total isn't always that high. I have seen it do that before. Here are some of my older results, which I had in a spreadsheet.

Given my SHGB is really high, and so is my total, what would people recommend? Do nothing? I am really not sure where to look since my condition seems pretty rare, or at least I haven't been able to find anything.

 

[Systemlord]

Given my SHGB is really high, and so is my total, what would people recommend? Do nothing?

SHBG is one of the most difficult hormones to influence.