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Patel P, Fantus R, Lokeshwar S, et al. Trends in Serum Testosterone Levels Among Adolescent and Young Adults Men in the United State. Presented at: 2020 AUA Virtual Experience; May 15, 2020. Abstract MP78-01.
Potential causes for these declines could be increased obesity/BMI, assay variations, diet/phytoestrogens, declined exercise and physical activity, fat percentage, marijuana use, and environmental toxins.
Environmental toxins?
Chemicals (including parabens and phthalates) in our environment are disrupting our hormonal balance, causing various degrees of reproductive havoc on a daily basis. These are called hormone or endocrine disrupting chemicals – also known as EDC’s
There certainly has been an increase in the use of plastics where phthalates are found.
Men, women and children exposed to high levels of phthalates - endocrine-disrupting chemicals found in plastics and some personal care products – tended to have reduced levels of testosterone in their blood compared to those with lower chemical exposure, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM).
pubmed.ncbi.nlm.nih.gov
How about Fluorides?
I was discussing this very subject with my doctor and he threw in the idea of fluorides. Perhaps he has a point:
Duan L, Zhu J, Wang K, Zhou G, Yang Y, Cui L, Huang H, Cheng X, Ba Y. Does Fluoride Affect Serum Testosterone and Androgen Binding Protein with Age-Specificity? A Population-Based Cross-Sectional Study in Chinese Male Farmers. Biol Trace Elem Res. 2016 Dec;174(2):294-299. doi: 10.1007/s12011-016-0726-z. Epub 2016 May 6. PMID: 27154732.
Furthermore, younger farmers, 18-29 and 30-39 years old, may be the most likely to have lower T levels when exposed to fluoride (P < 0.05).
pubmed.ncbi.nlm.nih.gov
More
Bai R, Huang Y, Wang F, Guo J (2020a) Associations of fluoride exposure with sex steroid hormones among U.S. children and adolescents, NHANES 2013–2016. Environ Pollut 260:114003
Research suggests that fluoride exposure may influence reproductive health among youth. A recent NHANES study found that higher plasma fluoride levels were associated with lower testosterone, estradiol and serum hormone binding globulin (SHBG) levels in adolescent boys as well as lower SHBG in girls.
www.sciencedirect.com
Potential causes for these declines could be increased obesity/BMI, assay variations, diet/phytoestrogens, declined exercise and physical activity, fat percentage, marijuana use, and environmental toxins.
Environmental toxins?
Chemicals (including parabens and phthalates) in our environment are disrupting our hormonal balance, causing various degrees of reproductive havoc on a daily basis. These are called hormone or endocrine disrupting chemicals – also known as EDC’s
There certainly has been an increase in the use of plastics where phthalates are found.
Men, women and children exposed to high levels of phthalates - endocrine-disrupting chemicals found in plastics and some personal care products – tended to have reduced levels of testosterone in their blood compared to those with lower chemical exposure, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM).
Urinary phthalate metabolites are associated with decreased serum testosterone in men, women, and children from NHANES 2011-2012 - PubMed
Because T plays an important role in all life stages for both sexes, future efforts should focus on better defining these relationships and their broader impacts.
pubmed.ncbi.nlm.nih.gov
How about Fluorides?
I was discussing this very subject with my doctor and he threw in the idea of fluorides. Perhaps he has a point:
Duan L, Zhu J, Wang K, Zhou G, Yang Y, Cui L, Huang H, Cheng X, Ba Y. Does Fluoride Affect Serum Testosterone and Androgen Binding Protein with Age-Specificity? A Population-Based Cross-Sectional Study in Chinese Male Farmers. Biol Trace Elem Res. 2016 Dec;174(2):294-299. doi: 10.1007/s12011-016-0726-z. Epub 2016 May 6. PMID: 27154732.
Furthermore, younger farmers, 18-29 and 30-39 years old, may be the most likely to have lower T levels when exposed to fluoride (P < 0.05).
Does Fluoride Affect Serum Testosterone and Androgen Binding Protein with Age-Specificity? A Population-Based Cross-Sectional Study in Chinese Male Farmers - PubMed
Many studies have demonstrated that exposure to excess fluoride was associated with a variety of diseases. Little is known about the variation of testosterone (T) levels caused by fluoride exposure. The aim of this study is to explore the association of fluoride exposure and age with serum T and...
pubmed.ncbi.nlm.nih.gov
More
Bai R, Huang Y, Wang F, Guo J (2020a) Associations of fluoride exposure with sex steroid hormones among U.S. children and adolescents, NHANES 2013–2016. Environ Pollut 260:114003
Research suggests that fluoride exposure may influence reproductive health among youth. A recent NHANES study found that higher plasma fluoride levels were associated with lower testosterone, estradiol and serum hormone binding globulin (SHBG) levels in adolescent boys as well as lower SHBG in girls.
Associations of fluoride exposure with sex steroid hormones among U.S. children and adolescents, NHANES 2013–2016
Fluoride mediated disruption of sex steroid hormones has been demonstrated in animals. However, evidence from humans was limited and contradictory, es…
www.sciencedirect.com
