Metformin Decreases Aerobic Capacity, Muscle Mass and Testosterone

[Deleted member 43589]

While all my T levels across-the-board tanked after starting metformin, my IGF-1 levels sharply increased from a baseline of 250 to almost 400 after taking tesamorelin, ipamorelin/CJC-1295. I am not on testosterone therapy at the moment and feel that anyone that is on metformin should be hormonally optimized.

Were you using TRT when your T levels dropped?

No doubt this is important for the "natural" guy but this may not matter much to steroid using exogenous testosterone who is already experiencing H.P.T.A. suppression.

 

[mcs]

Were you using TRT when your T levels dropped?

No doubt this is important for the "natural" guy but this may not matter much to steroid using exogenous testosterone who is already experiencing H.P.T.A. suppression.

No TRT while on metformin. My take: caution to euglycemic men in using metformin when not on TRT.