Lower Circulating Androgens Are Associated with Overall Cancer Risk and Prostate Cancer Risk in Men Aged 25–84 Years from the Busselton Health Study

madman

Super Moderator
In conclusion, in this population of community-dwelling men spanning a wide age range and followed for two decades, lower T and DHT were associated with an increased incidence of any (non-skin) cancer, whilst lower T was associated with an increased incidence of prostate cancer. No associations of androgens with lung cancer were observed; however, higher LH was associated with an increased risk of lung cancer. There were no associations of sex hormones with colorectal cancer incidence. Associations of low T and increased overall cancer risk may be reflective of poorer health status in these men. Further studies using LC-MS/MS-measured sex hormones are required to clarify the relationship between T and prostate cancer risk in men. Ongoing epidemiologic and mechanistic studies are required to validate findings of higher LH and lung cancer risk.
 

Attachments

Last edited:

Online statistics

Members online
1
Guests online
240
Total visitors
241

Latest posts

Back
Top