Definitely noticed a improvement in libido and overall well being when increased to 200mg. Estrogen. Mabey a little more water retention. I’m on losartan 200mg day. B/p. Averaged 125-130 in 150 mg. In 200mg. I average 135/80. Moody ness. My wife has always said I was moody and blamed the test. Me. My moody ness has always felt like a response to family and marriage
More interested in seeing where your trough FT level truly sits.
No point in posting FT unless it was tested using an accurate assay.
Too many get caught up on TT and although it is important to know FT is what truly matters as it is the active unbound fraction of T responsible for the positive effects.
As you should very well know from being on the forum long enough that men with lowish/low SHBG can run a lower TT and still achieve a healthy FT level.
With a TT 1000 ng/dL and lowish/low SHBG.....FT is going to be through the roof.
Mar 27, 2021
Labs from 75mg im every 3.5 days
Total. 7.33. 1.74-7.81
Free. 274. 47-244
Shgb. 20. 11-80
Your labs above from the previous protocol 150 mg T/week split (75 mg every 3.5 days).
As you can see your trough TT 733 ng/dL is far from what would be considered high and more importantly, with a lowish SHBG 20 nmol/L your FT is high although it was most likely not tested using an accurate assay and would most likely be closer to the upper end.
Again the only way to know where your FT level truly sits is to have it tested using the most accurate assays such as the gold standard Equilibrium Dialysis or Ultrafiltration (next best).
Even then on your most recent protocol 200 mg T/week split 3X (Tuesday Thursday Saturday) your trough TT 1044 ng/dL is on the higher end and seeing as you are waiting on your SHBG then I would say there is a good chance that your trough FT level is absurdly high as in almost 40 ng/dL (if SHBG is still 20 nmol/L) and for all we know you may have driven down your SHBG further which would have your trough FT even higher as you drove your T dose from 150 mg--->to a whopping 200 mg/week!
Top it all of that your trough estradiol (LC-MS/MS) is really high.
Why you would make such a significant jump in your T dose going from 150--->200 mg/week knowing you have lowish SHBG 20 nmol/L is beyond me.
When a protocol is tweaked (increase/decrease T dose) 12 weeks is needed to truly gauge how one feels regarding relief/improvement of low-T symptoms and overall well-being let alone whether one can state it was truly a success or failure.
If you truly feel well overall, minus sides and blood markers are healthy then I would not be too concerned if your FT is very high.
Definitely noticed a improvement in libido and overall well being when increased to 200mg.
This would be expected as you increased your weekly T dose drastically.
Even then I would put money on it that the boost in libido will be temporary and short-lived and will level off once blood levels have stabilized.
You may very well be one of the lucky ones if you end up maintaining a strong libido in the long run!
