My wife has started HRT with Defy about 7 weeks ago. For the time being she is using testosterone cream and DHEA/pregnenolone tablets nightly. She is having some irregular, longer lasting periods. We have notified Defy and are waiting to hear back from them. In the meantime she is looking for a helpful forum/website that may be as helpful to her as excelmale has been to me. Does anyone have recommendations? Thanks in advance.