Infrequent dosing to avoid shutdown…

[FunkOdyssey]

Thats very interesting, shame there is no date on the study.
Has there been other discussion on this trial?
Would be a great new tool in the tool box if this became available for sure.

They haven't published the trial yet but they're working on it. It's available now though, in Texas, California, Maryland, Florida, Ohio, West Virginia and Michigan. They're expanding availability to additional states quickly.

 

[Guided_by_Voices]

From the paper:
A low dose of oral testosterone undecanoate, dosed at 40 mg three times daily, combined with tamoxifen citrate, dosed at 10 mg twice daily, showed no adverse effects on pituitary or Leydig cell activity,

I don't think I would want to be on that long term... no? 20mg of Tamoxifen a day... ouch.

I think the point is that supplementing T while maintaining some degree of natural production is likely possible. Figuring out a sustainable protocol will require more crowdsourcing, but I would want to at least try this route if I was starting down the TRT road again.

 

[nippy]

Several things...Have you tried a low dose of clomid (e..g 12mg every other day or 25mg twice per week)? That should not be suppressive at all and should boost your T, however it sounds like it is some metabolite of T that persists for several weeks or possibly some sort of receptor up-regulation that is giving you benefit rather than just the T itself. Another option is to use the Gel and Clomid together which may not be suppressive at all. Bloodwork will give you a good indication but in general suppression is a due to a combination of the compound, dose, duration, and frequency of use. For example, some compounds (e.g. oxandrolone and (i think) turinabol) are not not particularly suppressive. Some of the very short-acting forms of T may be less suppressive and you can search here for @Cataceous 's posts which describe those. Lastly, I would use the term suppression rather than shutdown since what you are doing will almost certainly not come anywhere close to shutting you down. All that said, a lot of people never get the progress you have already so once a month or every three weeks seems very low risk for the foreseeable future.

Hi. I came off trt as it had no benefits on me. It's been 12 weeks and my LH has shot up but my free t is very low . My libido is still in the gutter as it was on trt. Would chlomid help my libido?

 

[Guided_by_Voices]

Hi. I came off trt as it had no benefits on me. It's been 12 weeks and my LH has shot up but my free t is very low . My libido is still in the gutter as it was on trt. Would chlomid help my libido?

It seems to for me, but I think it will differ by person since some people react negatively to it. You will likely have to give it a try and see how you react. I would start at a low dose like 12mg every other day of 25 mg twice per week.

 

[nippy]

It seems to for me, but I think it will differ by person since some people react negatively to it. You will likely have to give it a try and see how you react. I would start at a low dose like 12mg every other day of 25 mg twice per week.

How long do you take it for... A few months or always .. are there any significant side effects...

 

[Guided_by_Voices]

I have been taking it consistently at a low dose, but again, you will need to experiment. I have not had any side effects I can detect.

 

[nippy]

I have been taking it consistently at a low dose, but again, you will need to experiment. I have not had any side effects I can detect.

Thank you for the reply