Like I said in another tread, where I am now I can only get hold of enanthate. I remember when I was a patient at
Defy,
Dr Saya told me without HCG
I should inject cypionate EOD. Now enanthate has a lower half life BUT I can only get hold of 100mg ampules of enanthate.
Let me first say that on anathetate I've been feeling better (although it's been about a couple of months.) I've tried once a week 100mg injections and twice a week 50mg (throwing the rest of ampule out of course). With the former I felt better but the in the last day before injection I felt low. I saw an increase in body hair too. (The worst side effect of TRT for me.) I've been thinking of trying 100mg every 6 days but wanted to have a scientific opinion as well.
Depends on the individual and what injection frequency they feel better on.
There are some men who would do just fine injecting once weekly.
SHBG would play a role in whether one injects less/more frequently.
The main difference between the various injection protocols (once weekly, twice weekly, M/W/F, EOD, or daily) would be the peak--->trough levels and stability of serum levels throughout the week.
Many would prefer injecting twice weekly over once weekly.
Regarding half-life enanthate/cypionate are basically interchangeable.
Although you stated that on the former protocol of 100 mg/once weekly you felt better but hit a low point comes weeks end (trough) than you would most likely have done better on the latter protocol 50 mg twice weekly if you would have given it enough time let alone we have no idea what your TT/FT levels were at the trough as you did not post blood work as you may have very well needed a slight dose increase.
Also, keep in mind that gauging how you feel within the first 6 weeks of switching a protocol (dose or injection frequency) that it can be misleading as your blood levels will be in FLUX during the weeks leading up until they stabilize (4-6 weeks) and even then it will still take 2-3 months for the body to adapt and this is when you should TRULY gauge how you feel overall regarding relief/improvement of low-t symptoms and overall well-being.
As you should know blood work is critical.
Post up labs from both protocols if you had them done otherwise it is just a guessing game!
My SHBG hovers between 32-35 nmol/L and I have been injecting Delatestryl (enanthate) @ 150 mg/week (75 mg every 3.5 days) for almost 3.5 years no AI or hCG.
It is what has worked for me, fortunately.
For many, it can take time to find what works for them.
Never felt the need to inject more frequently as I feel great overall.