High Hematocrit: Effect on Blood Pressure & Effect of Altitude on Hematocrit

[Biobro]

Any idea how long it took for the reductions to take place?

Exposure and measurements
The baseline measurement period (non-exposure period) was defined as within 12 months before the start of ARB or CCB monotherapy. The exposure period (outcome measurement period) was defined as between 2 and 12 months after the start of ARB or CCB monotherapy. The mean exposure of ARB users and CCB users was 243.2 days and 242.1 days, respectively. Laboratory data, including serum levels of triglyceride (TG), total choles- terol (TC), non-fasting blood glucose, hemoglobin A1c (HbA1c), creatinine, sodium, potassium, alanine amino- transferase (ALT), aspartate aminotransferase (AST), and gamma-glutamyltransferase (GGT), hemoglobin, hema- tocrit, and white blood cell (WBC), red blood cell (RBC) and platelet (PLT) counts, were collected for each individ- ual at the date nearest the start of ARB or CCB mono- therapy in the baseline period, and at the date nearest 12 months after the start of ARB or CCB monotherapy in the exposure period.

 

[MarkP]

My Recent bloodwork:
MCV at 109 (outside healthy range) - too high.
How many times annually is reasonable to give blood without it being harmful to iron deficiency and energy loss etc.?

60 yr old.
TRT 10+ years
HCG 1 year

 

[tareload]

Stroke-Related Mortality at Different Altitudes: A 17-Year Nationwide Population-Based Analysis From Ecuador.

Living at higher elevation with higher hematocrit may decrease cardiovascular risk! https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525493/...

www.excelmale.com

 

[Nelson Vergel]

Another study connecting high blood pressure and hematocrit

Blood pressure responses to TRT are amplified by HCT levels in opioid-induced androgen deficiency

Our study aimed to examine the effect of testosterone replacement therapy (TRT) on blood pressure in opioid-treated men with relative hypogonadism, and whether the effect of TRT on blood pressure was modified by body composition, red blood cell levels, or carotid intima-media thickness. Men...

www.excelmale.com

 

[Gman86]

finally someone with a brain in this forum thinking outside the "iron" box and pays attention out there.

Appreciate this lol. Again, I’m still continuing to learn about iron and iron status within the body. Haven’t done research on it in a while tho. It’s definitely still a bit confusing. I know @Systemlord said he felt horrible with a ferritin level below something like 80, and is trying to get it up to around 100. Yet someone like Morley Robbins would probably say that a ferritin level this high is horrible for overall health.

What’s ur thoughts on iron status?

 

[Gman86]

My thoughts is similar to Morleys. 2 well written books exist out there on why we should focus on Copper and not iron.
By people who dedicated their lives to this research. And treat real live people daily. With great results. When people drain their blood they also drain their copper. And so much more. Yes we need Iron. But not in those dosages we are told.
The key is copper, not iron.
Off course people will shout out copper is toxic.
But im not going to debate this with a bunch of people in here. They can read for themselves if they wish to know:

Amazon.com

Amazon.com : copper book morley

Amazon.com

Ya copper is definitely an underrated mineral. Do u eat liver to make sure u get enough of it?

I didn’t know that we lose copper when giving blood/ losing blood. Good to know tho

 

[Gman86]

Yes I eat liver 3x week. one can overdose on it if daily.
Also you can buy Copper Sulfate Fine Crystals and dissolve it in 50/50 dmso and water and use transdermal. its so cheap you can provide your whole family for few $.
I also drink from copper cups. Water in 100% pure copper cups sitting for 6-8 hours is fully charged with ions and good energy.
I also put copper in my water storage tanks for the house. And few meters of pipe is made of copper.
Its disinfecting very well everything. Some people use copper as part of their swimming pool cleaning system.
Not to mention copper conducts electricity and is used in gardens for Electro Culture increasing yield of plant growth. My plants love it.
Wearing jewelry made of copper is good too.
Copper is a deep rabbit hole I could go down but it would be too "unscientific" for most minds in here to read
The books are just scratching the surface. Copper has many esoteric properties as well and they knew about this in ancient times.

Wow, u’ve definitely done ur homework! A man after my own heart lol. I sometimes feel like I get a little autistic with the way I research stuff, so I love how in depth u’ve gone into all the benefits of copper. I saved all this for future reference. Will definitely be giving copper more of a deep dive once when I have the time. Thanks so much for the detailed response tho!

How many ounces of beef liver do u eat each time? I usually do like 3.5oz of beef liver twice a week. So around 7oz total per week

 

[Vince]

Yes I eat liver 3x week. one can overdose on it if daily.
Also you can buy Copper Sulfate Fine Crystals and dissolve it in 50/50 dmso and water and use transdermal. its so cheap you can provide your whole family for few $.
I also drink from copper cups. Water in 100% pure copper cups sitting for 6-8 hours is fully charged with ions and good energy.
I also put copper in my water storage tanks for the house. And few meters of pipe is made of copper.
Its disinfecting very well everything. Some people use copper as part of their swimming pool cleaning system.
Not to mention copper conducts electricity and is used in gardens for Electro Culture increasing yield of plant growth. My plants love it.
Wearing jewelry made of copper is good too.
Copper is a deep rabbit hole I could go down but it would be too "unscientific" for most minds in here to read
The books are just scratching the surface. Copper has many esoteric properties as well and they knew about this in ancient times.

Have you ever had your copper levels check? I do supplement with zinc balance which includes copper.

Office of Dietary Supplements - Copper

Copper overview for health professionals. Research health effects, dosing, sources, deficiency symptoms, side effects, and interactions here.

ods.od.nih.gov

 

[Vince]

No I havent. Blood saturation of copper doesnt tell you whats going on in the cell.
I can feel what my body tells me. without copper it feels very different. ALso the dosages people think they need to thrive might be much higher than they think.
I recommend the books I linked to.

Copper Toxicity - StatPearls - NCBI Bookshelf

 

[Jim Marlowe]

@Cado, you are an interesting guy. Clearly knowledgeable. I realize blood serum copper levels don't speak to tissue saturations. But what about low serum copper levels combined with low ceruloplasmin levels? I ask because that's my situation. And full gene sequencing reveals I am heterozygous for a hypoceruloplasminemia condition. One might say that means nothing if it is a recessive mutation, but I think people now realize that the expression of these genes is not so simple as whether one has one or two copies. One might have reduced function that brings on the condition if one is heterozygous. In any case, copper-iron metabolism is so tricky. Low ceruloplasmin can mean copper toxicity, but what about where serum copper levels are low? Hard to find research on this, including with the Morley Robbins people. I supplement with copper and still have low serum levels.

 

[Vince]

@Cado, you are an interesting guy. Clearly knowledgeable. I realize blood serum copper levels don't speak to tissue saturations. But what about low serum copper levels combined with low ceruloplasmin levels? I ask because that's my situation. And full gene sequencing reveals I am heterozygous for a hypoceruloplasminemia condition. One might say that means nothing if it is a recessive mutation, but I think people now realize that the expression of these genes is not so simple as whether one has one or two copies. One might have reduced function that brings on the condition if one is heterozygous. In any case, copper-iron metabolism is so tricky. Low ceruloplasmin can mean copper toxicity, but what about where serum copper levels are low? Hard to find research on this, including with the Morley Robbins people. I supplement with copper and still have low

My understanding always has been that you must balance zinc with copper. I've never had either of my levels. But I do supplement with both zinc/ copper.

Zinc Information | Mount Sinai - New York

Learn about Zinc or find a doctor at Mount Sinai Health System.

www.mountsinai.org

 

[Jim Marlowe]

My understanding always has been that you must balance zinc with copper. I've never had either of my levels. But I do supplement with both zinc/ copper.

Zinc Information | Mount Sinai - New York

Learn about Zinc or find a doctor at Mount Sinai Health System.

www.mountsinai.org

Agree. I stopped supplementing zinc a long time ago, except as with an acute viral infection maybe once a year. My zinc levels are consistently within normal range, with copper and ceruloplasmin being low, as in very low normal or out of range low. Of course that is serum concentration vs. tissue concentration. And hacking test doesn't necessarily create benefits.