High E2. Not sure I care.

[MarkM]

Thanks for linking to this. Very interesting. Dr. Ramasamy doesnt seem to be too worried about treating E2 until it's over 60. And Dr. Saya seems okay with 45-50.

I will likely keep testing and see where mine settles.

Some people are extremely sensitive to rising E2 and come down with symptoms quickly at the hint of it increasing. Those people need an AI in many cases. Others with increasing E2 don't have symptoms because their body handles the increase in E2 just fine. Sometimes we want to treat E2 just because a number gets higher and maybe we should hold off introducing a new chemical into our body until we are symptomatic.

 

[mjb]

Just wanted to follow-up. Seems like doing nothing was the best plan. Things seem to be settling in nicely. Retested 3 months ago and then again last week.

E2 was 57.5 at last check. Still haven't touched the AI. Feeling great. Continuing to put on lean bodyweight, ~10 lbs total over past 6 months. Very pleased with strength, energy, libido, mood.

LABS
Pre-Clomiphene
Clomiphene/Anastrozole/DHEA
Testosterone/HCG/DHEA

Test, Serum: 305->788->886->1105->108-->934->1039->861->1131

Free T (Direct): 5->15.7->16.3 ->19.4->16.3->20.6->26.4->20.9->29.1

DHEA-Sulfate: 106->291.9->253->293.6->600.5->453.1

E2, Sensitive : 16.5 ->29.2 ->20.9->29.7->29.4->28.5->72.8->57.7->57.2->57.5

SHBG: 42->46.9->44->68->63->61.2->38.4->xx->29.6

T:E ratio: 18.5 ->26.8->41.43->37->36.8->32.77->14.3->15->19.7

Free:Total T: 1.6%->2%->1.8%->1.76%->1.5%->2.2%->2.5% ->2.4%->2.6%