Help! Insomnia, Irritability, and Libido Issues on TRT

[RickD]

Myj clinic put me on Arimidex to lower my E2 (they don't have a E2 sensitive test anywhere near me that I can find), half of the lowest pill they make, for a month now and my libido is so in the tank it's laughable...

 

[Ribeye]

Here's my most recent bloodwork with an SHBG of 38

I was on 250 mg test C split into daily injections as well as 150 IU HCG ED. I was also taking 100 mg pregnenolone before bed because my pre-TRT progesterone was 0.1

I have been waking up too early (after 6 hours in bed) and unable to go back to sleep + feeling mildly irritable and having problems with libido. My sexual interest is okay but my erections are absolutely laughable. It also seems to take me forever with stimulation to actually achieve orgasm.

I'd appreciate any help!

Based on these results I'm likely going to lower my test dose to 140 mg/week (still every day) and keep the HCG dose while dropping the pregnenolone.

View attachment 25287

I am not going to comment on your labs, aside from suggesting they are indeed very high numbers. I have been seeing a sexual medicine specialist, who has convinced me to lower my numbers for the same two reasons you seek help. Poor quality erections, lead to extended time to orgasm. There is more going on with erections than just testosterone, yes we all need it but after a certain amount erections don't continue to improve. Libido is more arguable, but again, in many men after a certain amount of T, low libido is likely something else as clearly it is multi factorial and involves brain chemistry too. My biggest point again, based on working with one of the best sexual medicine physician in the country, was lower my T dose, with numbers not nearly as high as yours, and see how you respond. I did, with her reassurance, and the doctor was right. Better erections, shorter time to orgasm and orgasm more often. All this despite having diagnosed ED. For each of us as individuals, some is good, more is not necessarily better, like me I suspect your levels got a little out of control for you. Don't be afraid to ask for a little help if you need to get the erections back on track, beyond just generic Cialis or viagra. The other options like Tri Mix and Quad mix really are easy, and can be extremely effective.

 

[AhmetAtay]

Lowering my E2 by taking aromasin/anastrozole did the job for me. Up to a solid 8/10 on erectile function. Expect it to continue improving as I get my numbers down.

 

[BJE]

Myj clinic put me on Arimidex to lower my E2 (they don't have a E2 sensitive test anywhere near me that I can find), half of the lowest pill they make, for a month now and my libido is so in the tank it's laughable...

I use Arimidex but the amount I use is 1/4 of a 1mg pill every two weeks. More than that is too much for me.

 

[BJE]

Lowering my E2 by taking aromasin/anastrozole did the job for me. Up to a solid 8/10 on erectile function. Expect it to continue improving as I get my numbers down.

That’s good to hear. In my experience even mildly high E2 lowers my penis sensitivity and makes orgasm difficult. I use that as a guide on when to take Arimidex. If I start to notice a loss of penis sensitivity I take 1/4 of an Arimidex pill. Any more than 1/4 pill every two weeks will drive my E2 down too low and I start to have other issues.

 

[AhmetAtay]

Interesting. Are you on HCG per chance? I'm beginning to suspect that's the real culprit here. I'm running 1050 IU HCG every week (150 IU ED). I'm going to try reducing it to 500 IU per week.