HCG Questions

[Vince Carter]

Some clarifications on this: The estradiol is a result of aromatase—"Leydig cells have a high capacity for aromatization and ... hCG can acutely stimulate aromatization independently of stimulating testosterone synthesis in vitro."[1] The reason this estradiol production is resistant to AIs is due to the high concentration of intratesticular testosterone relative to serum levels, ~40 times greater.[2] My assumption is that it's not practical to make intratesticular AI concentrations high enough to counteract this.

Excellent, thanks @Cataceous

 

[capozp]

So this week I started HCG. Monday the doc gave me the first shot in the office to show me how its done. 25 units. This doctor actually carried HCG (compounded pharmacy I assume). I will be injecting 25units 2X weekly, Mondays and Thursdays. I did feel a little weird after the shot, like I had too much coffee. But it quickly passed. That evening I felt a strange sensation in my testicles, almost like a mild case of blue balls. I wonder if it could be working so soon.
The powder in the vial is all stuck in the bottom. When I shake the vial it doesn't move at all. Is this normal?

This doesn't sound right. I get my HCG from EMPower and I have to mix the powder with Bacteriostatic water. You should not see powder on the bottom of the vial after mixing.

 

[Gman86]

This doesn't sound right. I get my HCG from EMPower and I have to mix the powder with Bacteriostatic water. You should not see powder on the bottom of the vial after mixing.

It’s just a matter of waiting an extra day for it all to dissolve. I use Empower as well. I had the box of HCG and bacteriostatic water in the fridge for a few days before reconstituting. I then reconstituted it, and there was white powder stuck to the bottom. I let it sit in the fridge for a day or two before using, and all the white powdery was dissolved.

 

[Vince]

So this week I started HCG. Monday the doc gave me the first shot in the office to show me how its done. 25 units. This doctor actually carried HCG (compounded pharmacy I assume). I will be injecting 25units 2X weekly, Mondays and Thursdays. I did feel a little weird after the shot, like I had too much coffee. But it quickly passed. That evening I felt a strange sensation in my testicles, almost like a mild case of blue balls. I wonder if it could be working so soon.
The powder in the vial is all stuck in the bottom. When I shake the vial it doesn't move at all. Is this normal?

I've never heard of that low of dose before. I wouldn't expect much from 25iu twice a week.

 

[SkyWarn]

I've never heard of that low of dose before. I wouldn't expect much from 25iu twice a week.

My bad, I meant 250units

 

[SkyWarn]

This doesn't sound right. I get my HCG from EMPower and I have to mix the powder with Bacteriostatic water. You should not see powder on the bottom of the vial after mixing.

No I haven't mixed it yet. I will be doing it tonight. What I meant was, the powder looks like its caked on the bottom. It doesn't move around when I shake the vial. BTW it appears that this is also from empower

 

[Charliebizz]

I do not think your supposed to shake hcg when reconstituted. You should gently roll it while mixing it.

 

[Vince]

When I mix my HCG with my BAC water. I just fill the vial with the BAC water and let it sit. I usually mix it a few days ahead of time, I let the powder and water mix on its own.

 

[Gman86]

When I mix my HCG with my BAC water. I just fill the vial with the BAC water and let it sit. I usually mix it a few days ahead of time, I let the powder and water mix on its own.

Exactly what I do, and it eventually all dissolves. Shaking it will destroy the HCG. I try not to even roll it too much. A good rule of thumb is, if you make any bubbles by shaking or rolling it, it’s destroying the HCG molecules. You never want to see bubbles.

 

[Greyfox]

Just got Pregnyl rx filled, whats this about it being discontinued?

 

[Airborne Warrior]

I've also just today bought 25000IU of Pregnyl so it's definitely not been discontinued.

 

[Gman86]

I've also just today bought 25000IU of Pregnyl so it's definitely not been discontinued.

You guys are getting me excited lol. I really hope they are still making it, as I would like to eventually go back on it if it’s availability becomes consistent again. My local pharmacy would be able to get it, then they wouldn’t for a month or two, then they would, etc. Are you guys sure that these aren’t bottles that were made a while back? I can still get Pregnyl from a compounding pharmacy around me, but they are the same bottles they’ve had for a while now. I heard that the manufacturer of Pregnyl stopped production, but I really hope that’s not the case.

 

[Gman86]

HCG/Pregnyl discontinued?

I obviously hope they’re still making it. I think it was at least discontinued at some point though, because GoodRX had coupons for Pregnyl for $113 at CVS forever, and then it jumped up to literally over $1000, no lie. Now it’s back down to what it was before. So maybe they discontinued it, and decided to start making it again. That’s at least what I’m hoping.

 

[Ardoc2]

Does not appear to be discontinued?
https://www.merckvaccines.com/INTER...Vaccines/Documents/files/Backorder_Report.pdf
I was told quite a while go it was discontinued as well..... but I think that means 'we no longer carry it and we want you to use our alternative rather than look for it elsewhere'

 

[Gman86]

Does not appear to be discontinued?
https://www.merckvaccines.com/INTER...Vaccines/Documents/files/Backorder_Report.pdf
I was told quite a while go it was discontinued as well..... but I think that means 'we no longer carry it and we want you to use our alternative rather than look for it elsewhere'

Those slick motherfckrs! Lol. I think you’re probably right. I think CVS was tired of me special ordering it or something, as they don’t usually stock it. Or maybe Merck fell behind in production for a while or something. It even says that it is still “backordered”. Either way, looks like they are definitely still manufacturing it. So thank you very much for that! I didn’t realize you could just look it up on their website like that. I obviously feel stupid for not thinking of that lol.

 

[Airborne Warrior]

Drug Shortage: Shortage of human chorionic gonadotropin for injection

 

[Tommy Wall]

Where I live I can only get Orvitrelle but I´m almost convinced it´s not as effective as Pregnyl.

 

[Jeromefrance]

Where I live I can only get Orvitrelle but I´m almost convinced it´s not as effective as Pregnyl.

It is effective. At Least for me...

 

[Tommy Wall]

Well for me its the only option and its ok but I prefered Pregnyl. Bigger sack with same 500iu.