Did anyone in particular at Defy make that statement about progesterone? I'd like to know the reasoning. I have discussed my supplementation with Jill, and it sounded like they'd have no objections to prescribing it.My DHEA is mid range, but my progesterone is completely undetectable. Supplementing 30mg pregnenolone raises my progesterone to 0.2, but even 10mg of preg makes me so tired I can't function, and Defy told me not to replace progesterone directly in males. I assumed it had a function, but honestly the information available is so confusing and contradictory that I can't seem to find an answer or anything that works. HCG would be very convenient but I don't think it actually raises downstream hormones, I've never seen that in my labs, and it has its own problems for me like excessive E2.
There's research showing that hCG is more likely to increase these hormones in younger men. Like you I never saw a bump while using it, and I also had the E2 issues.