DRY EYES

geyxsx · Feb 10, 2025

Hello Guys-
I know you guys are the the expert on all things TRT, but I really need your help on this one.
I'm on TRT for 2 years and suddenly starting having really dry eyes to the point of needing to see a dry eye specialist. You guys have seen it all. Could this be TRT / Estrogen related ? I'm on 28mg IM q 2 days with only 200 IUs hcg twice a week.
Testosterone is 600-800 and estrogen is around 17-30. Varies, but last one was 17 when the dry eyes was pretty bad. This actually started when I was trying to go down on my dose and I had cut out the hcg, but I'm not sure anymore if it's related to my hormones at all, but just wanted to see if you have seen any patterns or experienced anything yourself?

I've always questioned if high or low estrogen is the cause of this.

geyxsx · Feb 12, 2025

Just reading how Testosterone can cause hypersecretory seborrhea MGD. (especially if you are acne prone- which I am)
@Nelson Vergel would you know anything about this?
I'm considering quitting TRT to see if this will help improve my dry eyes although I'm aware low testosterone can also do the same, but I didn't have dry eyes before starting TRT

Nelson Vergel · Feb 13, 2025

Thread 'Testosterone and meibomian gland (eyelid) dysfunction'

Jun 13, 2021

Abstract

The meibomian gland, the largest sebaceous gland of the body is responsible for the biosynthesis of the lipid layer of the tear film to prevent excessive evaporation. The loss of normal functions of the meibomian gland, known as meibomian gland dysfunction (MGD), is a chronic disease and is the leading cause of dry eye symptoms in clinics. Studies have found sex hormones, especially androgen, play vital roles in the regulation of the functions of the meibomian gland. Recently, androgen has also been preliminarily applied in clinics for the treatment of MGD and showed...