BadassBlues
Well-Known Member
Dr. Mariano knew the correlation between testosterone and dopamine. His posts and research on the subject were amazing.BTW , best knowledged ever .
Dr. Mariano knew the correlation between testosterone and dopamine. His posts and research on the subject were amazing.BTW , best knowledged ever .
Yes his posts were amazing. Amazing enough for me to book a consultation with him.Dr. Mariano knew the correlation between testosterone and dopamine. His posts and research on the subject were amazing.
Yes, I also have the same experience sadly. Also the doctor who you get to talk to about hormones is a dermatologist and he seems very incompetent, arrogant and not interested in what you have to say. The average bodybuilder on roids seems to know more sadly...Thierry Hertoghe is overrated. He isn't up to date on the current, modern trt-practices. He prescribes test E injections every 2-3 weeks and an AI to anyone above the range of estradiol.
I have a friend who's currently living in Belgium who went to the Hertoghe Clinic. He told me the Hertoghe Clinic apparently has two sides: the public side of Thierry talking passionately about hormone therapy and the money grabbing side of his uninterested doctors - Thierry himself only does consultations with high profile clients - who give everyone the standard protocol. They order expensive blood tests but don't actually do anything of importance with them. They don't track you but they still want regular appointments just to earn a paycheck.
Yes the nice Dr H in the vids is misleading, the clinic is very different, I got the impression it was get the cash, yes cash, and out the door you go, far from ethical. I think they prescribe so much stuff because they get a kick back from the pharmacy. its a pity because Dr H may know a lot of stuff, but his main thing is making money out of "training" other docs and selling video courses and books and touring the world doing seminars. He has hard selling vids on youtube as if he was selling double glazing windows or used cars. Its become a bit pharsical. I think he is good at anti aging regimes for himself but I dont think they care about patients, that was my impression having been there a few times. The thing is he has a monopoly in Europe , its not like the US where their is a choice.Yes, I also have the same experience sadly. Also the doctor who you get to talk to about hormones is a dermatologist and he seems very incompetent, arrogant and not interested in what you have to say. The average bodybuilder on roids seems to know more sadly...
Also it's clear their focus is on old women getting botox, and other "longevity" grifting. That's where they make the real money. But men with hormonal problems? Hardly any money in that. Even saw some people comment that they advise some people there a sh*t ton of supplements and herbs that cost thousands of dollars/month...
The youtube videos of Hertoghe are a facade. It's really sad though, hardly any good endos on mainland europe.
But I have to mention that @K.pietera did have a good experience with Hertoghe clinic though.
Yes his posts were amazing. Amazing enough for me to book a consultation with him.
Too bad that he's far from the amazing doctor he appeared to be online!
Oh wow, so it resolved the anhedonia completely, and got u back to ur baseline before using PT-141?Yea, I went to him after a severe reaction to PT-141 a melanocortin peptide years ago which gave me severe anhedonia. He pretty much did not know what was going on. It did not fit into his HPA axis theories at all, bloodwork looked fine. He just told me it was psychosomatic eventually. Useless.
I ended up needing ECT. He was negative about it but I got it from another doc and it worked like a charm.
Oh wow, so it resolved the anhedonia completely, and got u back to ur baseline before using PT-141?
how many ECT sessions did u do?
Awesome. Thank u so much for the detailed response. I appreciate it more than u know. And I agree, imo depression and anhedonia are two of the worst conditions for sure. Unless u’ve experienced both, u really can’t even begin to understand what it’s like to not only not feel any pleasure from anything in life, but to then feel depressed and feel like there’s 100% no hope of anything ever getting better is just absolute torture 24/7. If u’ve experienced that combo, it’s extremely understandable why some people that deal with these conditions commit suicide. I don’t blame them whatsoever. It can be literal torture simply waking up and having to go through another full day feeling those ways.Yea it did, back in Feb/Mar 2018. I dont recall exactly but it was like 12 or so sessions. I remember with unilateral was first 6 and that mainly helped anxiety a lot but I needed bilateral and after the 2nd bilateral coming home sleeping and waking up like a switching was flipped. Then I needed a few more to make it stick. My symptoms were basically akin to severe PSSD/PFS just from 1 injection of 200 mcg. The thing was hell for my body. In 2 hours got severe anhedonia with the hard on. And constant severe nausea and agitation.
Was recommended ECT because when my normal doc (not Dr M) put me on nortrip it just blunted me more, abilify made me restless He then said “all med reactions are unpredictable just do ECT”. My doc had PFS/PSSD patients for whom it worked for and thought it would work for this too. And I was desperate so I did and it paid off. I ended up with just some foggy memory of the time I got it but otherwise cognitively I was totally fine in a month, and back to grad school in 2 weeks.
The first ECT center I tried called me bipolar psychotic for injecting PT141 and said I needed to be injected antipsychotics not ECT. So I tried another place and they were willing
Even still that year I would have random dips but I would take a Klonopin+Modafinil to kinda reset them. Post orgasm id still feel kinda blunted too for like a day but over time this resolved. The worst crash was when I smoked weed (indica strain) once and it just completely numbed me, a reaction I never had prior to PT141. Thankfully subsided in a week. I completely swore off all drugs after that outside social drinking and caffeine. I was fine from 2018-aug 2022, basically 4 years no issues.
However now years later in 2022 last year the 2 drugs (alcohol and caffeine) that were ok suddenly became problematic too. In july 2022 I got covid and I was fine but then in August a fucking alcohol hangover retriggered anhedonia that never happened before. I was recovering in a week but then guess what caffeine crashed me suddenly emotionally blunted me and I became sensitive to anything noradrenergic since. Although pure dopamine or precursors are ok, and armodafinil helps a bit but has tolerance. Thankfully my anhedonia is just moderate-mild this time, and doing monthly cycles of MIF-1 seems to help me.
Turns out I have dysbiosis too. But hormonally things are still fine. They did get impacted by the stress of this problem but changes in TRT dont affect my symptoms either way.
So yea PT141 seems to have permanently planted a vulnerability to anhedonia.
It pisses me off so much and its why im so triggered and get kind of “passionate” about anhedonia symptoms. Its quite possibly the worst condition imo to have, and having simple hormonal HPA low mood/anxiety issues is nothing in comparison. And few doctors even understand anhedonia-blunting as its own condition.
Dr M was not helpful at all for anhedonia.
It also surprises me how much can induce anhedonia in vulnerable people, even Ashwagandha or NAC can do it. On this forum I even read of Tamoxifen or Arimidex doing it. Ironically, TRT despite all the scare stories turns out to be safer than all this in terms of not having this side effect.
Oh very interesting I have PFS. ECT is electroshock right? How does that work?He then said “all med reactions are unpredictable just do ECT”. My doc had PFS/PSSD patients for whom it worked for and thought it would work for this too. And I was desperate so I did and it paid off.
Thank you for the details of what you were experiencing from PT-141 and your response to ECT. I have treatment resistant bipolar/mixed state, non-restorative sleep & CPTSD. Anhedonia is ever present in my life. My psychiatrist suggested ECT but as I'm caring for my wife, who is into her 17th month of rapidly progressing Alzheimer's, I need to be present and functional, so I just limp along, emotionally, day after day.Yea it did, back in Feb/Mar 2018. I dont recall exactly but it was like 12 or so sessions. I remember with unilateral was first 6 and that mainly helped anxiety a lot but I needed bilateral and after the 2nd bilateral coming home sleeping and waking up like a switching was flipped. Then I needed a few more to make it stick. My symptoms were basically akin to severe PSSD/PFS just from 1 injection of 200 mcg. The thing was hell for my body. In 2 hours got severe anhedonia with the hard on. And constant severe nausea and agitation.
Was recommended ECT because when my normal doc (not Dr M) put me on nortrip it just blunted me more, abilify made me restless He then said “all med reactions are unpredictable just do ECT”. My doc had PFS/PSSD patients for whom it worked for and thought it would work for this too. And I was desperate so I did and it paid off. I ended up with just some foggy memory of the time I got it but otherwise cognitively I was totally fine in a month, and back to grad school in 2 weeks.
The first ECT center I tried called me bipolar psychotic for injecting PT141 and said I needed to be injected antipsychotics not ECT. So I tried another place and they were willing
Even still that year I would have random dips but I would take a Klonopin+Modafinil to kinda reset them. Post orgasm id still feel kinda blunted too for like a day but over time this resolved. The worst crash was when I smoked weed (indica strain) once and it just completely numbed me, a reaction I never had prior to PT141. Thankfully subsided in a week. I completely swore off all drugs after that outside social drinking and caffeine. I was fine from 2018-aug 2022, basically 4 years no issues.
However now years later in 2022 last year the 2 drugs (alcohol and caffeine) that were ok suddenly became problematic too. In july 2022 I got covid and I was fine but then in August a fucking alcohol hangover retriggered anhedonia that never happened before. I was recovering in a week but then guess what caffeine crashed me suddenly emotionally blunted me and I became sensitive to anything noradrenergic since. Although pure dopamine or precursors are ok, and armodafinil helps a bit but has tolerance. Thankfully my anhedonia is just moderate-mild this time, and doing monthly cycles of MIF-1 seems to help me.
Turns out I have dysbiosis too. But hormonally things are still fine. They did get impacted by the stress of this problem but changes in TRT dont affect my symptoms either way.
So yea PT141 seems to have permanently planted a vulnerability to anhedonia.
It pisses me off so much and its why im so triggered and get kind of “passionate” about anhedonia symptoms. Its quite possibly the worst condition imo to have, and having simple hormonal HPA low mood/anxiety issues is nothing in comparison. And few doctors even understand anhedonia-blunting as its own condition.
Dr M was not helpful at all for anhedonia.
It also surprises me how much can induce anhedonia in vulnerable people, even Ashwagandha or NAC can do it. On this forum I even read of Tamoxifen or Arimidex doing it. Ironically, TRT despite all the scare stories turns out to be safer than all this in terms of not having this side effect.
@electrify did u experience any memory loss, that ur aware of, from ur ECT treatments?
Thank you for the details of what you were experiencing from PT-141 and your response to ECT. I have treatment resistant bipolar/mixed state, non-restorative sleep & CPTSD. Anhedonia is ever present in my life. My psychiatrist suggested ECT but as I'm caring for my wife, who is into her 17th month of rapidly progressing Alzheimer's, I need to be present and functional, so I just limp along, emotionally, day after day.
She's not the first doctor to discuss ECT. When we lived in Maryland, a noted psychiatrist at the NIH, whom I was going to, gave me a referral to a doctor who did ECT, exclusively, but I was(and still am)fearful of significant memory loss. But, again, ECT is moot at this time.
Also on TRT and for a day or two after my injection, my mood is a bit better. Currently doing 70 mg 2X weekly but wondering if 50 mg 3X weekly might be better. However, without consistently restorative sleep, with or without mood problems, you can't feel mentally or physically good.
I think that is what you have to pay to see Hertoghe in person. He only sees a few patients himself, and you will probably be followed by another doctor in his clinic. A few years ago, H charged €2000 for a private consultation. I paid €350 a year ago for a one hour consultation with one of his colleagues. A complete waste of money. Those doctors are charlatans IMO. I have not seen H, but if he works like the other doctors in his clinic, you will end up on a very strong hormone cocktail and pay a fortune just to have prescriptions renewed. There is no proper follow-up, and those doctors are not competent enough to deal with side effects. The doctor I saw is a family doctor (GP) in Brussels. What makes such a doctor qualified to prescribe growth hormone…?! I think that children on GH are treated by specialists.After watching a video of Dr. Hertoghe on YT I decided to call the clinic to take an appointment. They told me Dr. Hertoghe fee is 3600 euro!!! Three- thousand-six- hundred euro! I’m not joking… WTF!
In the other comments I saw here the fee for a consultation was super cheap in comparison, what the heck happened in the meantime?
Same experience as you. That clinic is a joke, don't be deceived by the youtube videos.I think that is what you have to pay to see Hertoghe in person. He only sees a few patients himself, and you will probably be followed by another doctor in his clinic. A few years ago, H charged €2000 for a private consultation. I paid €350 a year ago for a one hour consultation with one of his colleagues. A complete waste of money. Those doctors are charlatans IMO. I have not seen H, but if he works like the other doctors in his clinic, you will end up on a very strong hormone cocktail and pay a fortune just to have prescriptions renewed. There is no proper follow-up, and those doctors are not competent enough to deal with side effects. The doctor I saw is a family doctor (GP) in Brussels. What makes such a doctor qualified to prescribe growth hormone…?! I think that children on GH are treated by specialists.
The other doctors` fees are not cheap either. €350 for an hour with an ignorant GP is way too much. After my visit last year, I cannot believe that so many patients are willing to waste money on them. But, since they are still around, that must be the case.