Dr. Samuel Denmeade on Bipolar Androgen Therapy for Prostate Cancer

[madman]

* This approach involves administering high doses of testosterone, which has shown significant improvement in 30% of patients, enhancing strength, energy, and sexual function

* their research uses blood-based DNA markers to predict which patients will respond best, aiming to personalize treatment and switch between high and low testosterone levels to prevent cancer resistance

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Dr. Samuel Denmeade, an oncologist at Johns Hopkins, discusses bipolar androgen therapy, a novel treatment for prostate cancer patients resistant to standard hormone therapy. This approach involves administering high doses of testosterone, which has shown significant improvement in 30% of patients, enhancing strength, energy, and sexual function. Dr. Denmeade explains how their research uses blood-based DNA markers to predict which patients will respond best, aiming to personalize treatment and switch between high and low testosterone levels to prevent cancer resistance.

 

[madman]

Identifying Blood-Based Markers for Optimized Bipolar Androgen Therapy in mCRPC

Samuel Denmeade, MD, of Johns Hopkins University School of Medicine, highlights his research on blood-based markers of differential efficacy of bipolar androgen therapy and enzalutamide in the randomized TRANSFORMER trial. This research was presented as a late-breaking abstract at the 2024...

www.excelmale.com

 

[Vince]

Could More Testosterone Be the Hidden Key to Fighting Prostate Cancer?

Androgen deprivation therapy (ADT) has been the bedrock of treatment for advanced prostate cancer for more than half a century. But investigators at Johns Hopkins are rethinking it – in a way that sounds counterintuitive – and driving new approaches to tackle treatment resistance. They’re...

www.pcf.org